Subcutaneous Mycoses

Question 1

How are lesions/pathologic effects of subcutaneous mycoses able to spread throughout the body?

Answer 1

Lymphatic channels

Question 2

Resulting lesions of subcutaneous mycoses are all ___ lesions.

Answer 2

Granulomatous

Question 3

Causative agent of Rose gardener’s disease

Answer 3

Sporothrix schenkii

Question 4

How do etiologic agents of subcutaneous mycoses enter the body?

Answer 4

Traumatic inoculation

Question 5

false about Sporothrix schenkii
A. branching and septate hyphhae
B. hyphae arranged in flowerlike clusters
C. dimorphic fungus
D. with neuraminidase

Answer 5

B

conidia dapat

Question 6

Which is not a means of entry for Sporothrix schenkii?
A.animal or insect bites
B.splinters
C.contaminated wound dressings
D.sexual contact

Answer 6

D

Question 7

Rose gardener’s disease produces lesions usually found at (A) for adults and (B) for kids

Answer 7

(A) lower extremities

(B) face

Question 8

this type of sporotrichosis cases is found in ~75% of cases; it forms sporotrichiotic chancre

Answer 8

lymphocutaneous sporotrichosis

Question 9

in chronic sporotrichosis, what happens to the lymph channels?

Answer 9

become hard and cord-like

Question 10

most reliable way to diagnose S.schenkii

Answer 10

culture (thermal conversion)

Question 11

T or F. Serology is still very helpful in sporotrichosis diagnosis.

Answer 11

F

Question 12

Exophiala jeanselmei
Pseudolescheria boydii
Madurella mycetomatis
Madurella grisea

these cause what specific mycoses?

Answer 12

mycetoma

Question 13

what is mycetoma?

Answer 13

it is interconnecting and it drains sinuses

Question 14

best way to diagnose mycetoma

Answer 14

culture

Question 15

false about Madurella morphology
A. white granules
B. air space
C. club-shaped hyphae

Answer 15

A

black dapat

Question 16

Phialophora verrucosa
Fonsecaea pedrosoi/compacta
Cladosporium carrionii
Rhiniocladiella aquaspersa

All these may cause what specific mycoses?

Answer 16

chromoblastomycosis

Question 17

all EAs of chromoblastomycosis have what color of hyphae?

Answer 17

dematiaceous/dark

Question 18

Pathogenesis of Chromoblastomycosis

1. tissue prolif
2. wartlike lesion
3. ______________

Answer 18

cauliflower nodules

Question 19

sclerotic bodies may be found in what specific mycoses?

Answer 19

chromoblastomycosis

Question 20

Rhiniocladiella aquaspersa & Fonsecaea pedrosoi : type of conidation

Answer 20

acrotheca

Question 21

Which has smaller conidia?

Fonsecaea pedrosoi/compacta

Answer 21

Fonsecaea compacta

Question 22

Causative agent of Entomophthoromycosis

Answer 22

Conidiobolus coronatus

Question 23

False about Conidiobolus coronatus
A.slow growing colony
B.zygomycete
C.non-septate hyphae

Answer 23

A

fast dapat

Question 24

Entomophthoromycosis - where does swelling begin?

Answer 24

nasal area

Question 25

in media w/o ____, spherical conidia with numerous branching hyphae are seen. for Conidiobolus coronatus

Answer 25

cyclohexamide

Question 26

common about epidemiology of Lobomycosis,Entomophthoromycosis and Sporotrichosis

Answer 26

more prevalent in males

Question 27

sequelae of germination of sporangiospores in nasal passages; may be caused by Rhizopus

Answer 27

Rhinocerebral mucormycosis

Question 28

Rhinocerebral mucormycosis may lead to what ocular complication?

Answer 28

orbital cellulitis

Question 29

inhalation of sporangiospores may lead to. __

Answer 29

thoracic mucormycosis

Question 30

morphology of mucormycosis EA @ H&E stain

Answer 30

infrequently septate, thin-walled hyphae, with irregular branching

Question 31

causative agent of rhinosporidiosis. Can it be cultured?

Answer 31

Rhinosporidium seeberi

no

Question 32

What is rhinosporidiosis?

Answer 32

chronic granulomatous disease of mucocutaneous tissue.nose: main target

Question 33

Lacazia loboi causes lobomycosis and is cross antigenic with ___

Answer 33

Paracoccidioides brasilienses

Question 34

lesions of lobomycosis resemble what bacterial infection?

Answer 34

leprosy

Question 35

When Lacazia loboi is mounted on Periodic Acid Schiff stain, what can be seen?

Answer 35

yeast cells inside macrophages

Question 36

Which geographic subpopulation has the most number of lobomycosis?

Answer 36

Calabi Indians

Question 37

What do Alternaria and Curvularia cause? (specific type of mycoses)

Answer 37

cause Phaeohyphomycosis

Question 38

False about EAs of Phaeohyphomycosis
A.dematiaceous with aseptate hyphae
B.black fungi in fruits
C.mycelia in morphology

Answer 38

A

with septa

Question 39

Identify causative agent of Phaeohyphomycosis

• macro: yeastlike, with short aerial hyphae
• micro: rocket-shaped mature conidiogenous cells with tapering zones

Answer 39

Exophiala jeanselmei

Question 40

T or F

Exophiala spinifera’s optimal temperature for growth is 40 deg C

Answer 40

F

It does not grow at 40 deg C

Question 41

Special medium where Cladophialophora bantiana grows

Answer 41

Potato Dextrose Agar

Question 42

causative agent of cerebral phaeohyphomycosis

Answer 42

Cladophialophora bantiana

Question 43

Enumerate causative agents of SubCT Phycomycosis

Answer 43

Basidiobolus haptosporus

Basidioolus ranarum

Question 44

False about microculture for Basidiobolus haptosporus //
Basidioolus ranarum
A. invaded vasculature
B. branching hyphae with infrequent septa
C. giant cells with multiple granulomata
D. inhibited by cyclohexamide

Answer 44

A

vasculature not invaded