Testis Cancer Flashcards
1
Q
Pathopneumonic Genetics
A
Isochromosome 12p
2
Q
5 Causes Elevated AFP
A
Non-seminomatous germ cell tumor Neural tube defects/ataxia telegiectasia Nonmalignant liver ds w/ regen (chronic hepatitis) GI neoplasms (gastric, panc, biliary) Non-GI tumors metastatic to liver
3
Q
Extra-embyronic Tumor Markers
A
Choriocarcinoma produces BhCG and yolk sac produces AFP
4
Q
AFP and BhCG Half Lives
A
5-7 days vs. 18-24 hrs
5
Q
IGCCCG Classification Important Factors
A
Visceral organ involvement or no, and tumor marker count
6
Q
Testis Chemo
A
PVB (cisplatin, vinblastine, bleiomycin) or BEP (etoposide, maybe a little better, less toxicity)
