Common Pathogen Flashcards
1
Q
HSV1/2 Transmission
A
Close contact (2- typically sexual)
2
Q
Varicella Zoster Virus VSV Transmission
A
Contact or respiratory route
3
Q
Cytomegalovirus CMV transmission
A
Contact blood transfusion, transplantaion, congenital
4
Q
General structures of herpesviridae
A
dsDNA, icosahedral capsid - surrounded by glycoprotein rich envelope
5
Q
herpesviridae entry
A
Attach/bind to surface protein (receptor) host cell - fusion of viral/host membrane
6
Q
herpesviridae Nuclear transport
A
Cellular microtubules
Genome enters through nuclear pores
7
Q
herpesviridae genes
A
Immediate early gene
Early gene
Late gene
8
Q
IE genes code for:
A
Expressed prior to protein syn (brought in)
9
Q
E genes code for:
A
DNA replication - vDNA pol, TK, helicase…
10
Q
L genes code for
A
structural proteins - capside/glycoproteins
