Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

DD/BL unit 3 > Dermal structures and diseases > Flashcards

Dermal structures and diseases Flashcards

1
Q

Dermis ranges in thickness from ___-___mm

A

1-4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Epidermis gets nutritional support from dermis because

A

no blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Downward projectin of epidermis is known as ________?

A

epidermal rete

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Epidermal rete interdigitate with upward projection of the ______

A

dermal papillae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

epidermal rete interlock with dermal papillae for ______ and _____

A

strength of adherence

Increases the surface area = nutritional to epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Epidermal ridges = aka ?

A

fingerprints

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Dermis is composed predominately of ____, ____, and ____

A

collagen fibers, elastic fibers, ground substance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Most common type of collagen?

A

type 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Collagen type in fetal dermis

A

type 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Collagen ___ in basement membrane zone in the ____ junction

A

4

dermoepidermal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Collagen __ attaches epidermis to dermis

A

7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Procollagen synthesized ____ within ___

A

intracellulary

fibroblasts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Procollagen structures

A

3 separate chain (alpha helical Gly-X-Y proline/hydroxyproline)
Straition 68 intervals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Procollagen chain are Gly-X-Y; X/Y typically?

A

proline

hydroxyproline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Collagen fibrils assembled ____

A

extracellularly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Co factors required to synthesize collagen fibrils ___

A

vitC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Deficient vit C is called ___ and symptoms includes:

A

scurvy

fail to heal, abn hair, fragile BV, teeth fall out

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Scurvy is a classic example of ____ in ____

A

acquired abnormality in collagen production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Ehlers-Danols syndrome (EDS) is a group of related disorder of _____

A

collagen synthesis

COngenital abnormality in collagen formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

4 major clinical features of ehlers Danlos syndrome

A

skin hyperextensibility
joint hypermobility
tissue fragility
poor wound healing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Collagen fibers provide skin with _____; elastic fibers provide skin with ___

A

tensile strength; resiliency (ability to return)

22
Q

collagen fibers form large eosinophilic/basophilic bundles?

A

eosinophilic

23
Q

Elastic fibers are ____philic?

A

argyrophilic - silver stains

24
Q

Solar elastosis is:

A

acquired disorder of elastic

25
Q

Accumulation of significant sunlight exposure leads to ______, appear ___ staining material under microscope

A

degeneration of elastic fibers

basophilic

26
Q

pseudoxanthoma elasticum PXE is a _______ disorder

A

inherited elastic disorder

27
Q

PXE is caused by a mutation in gene encoding for _____

A

multidrug resistance complex

28
Q

In PXE, elastic fibers of dermis become ____ and results in a characteristic ____ color

A

enlarged, tangled, calcified
purple blue color
(elastic fibers in BV also damaged - hypertension/bleeding disorder in eye)

29
Q

Ground substance is used to describe ____

A

gelatinous material between collagen bundles, ealstic fibers, appendageal structures of dermis

30
Q

Two glycosaminoglycans:

A

hyaluronic acids, dermatan sulphate

31
Q

Ground substance produced from ____

A

fibroblasts

32
Q

Pure hyaluronic acid can be used to ___

A

costmetic filler

Natural substance that absorbs a lot of water

33
Q

Suprapapillary plate =

A

capillary structures in skin in uppermost portion of papillary dermis

34
Q

Auspitz sign

A

remove thickened scales of poriasis = pinpoint bleeding

35
Q

Warts = aka ?

A

Verruca - benign - virally induced neoplasm = increase dblood supply

36
Q

Leukocytoclastic vasculitis involves ____

A

post capillary venules because of immune complexes

Strep, allergy/hep C

37
Q

Vasculitis manifest as _____

A

palpable purpura

38
Q

unmyelinated C fibers with a ________ rate; after entering spinal cord with ___ neurons whos axons cross to opposite site of body

A

slow conduction

secondary

39
Q

Congenitla insensitivity to pain mutation in _____?

A

neurotrophic tyrosine receptor kinase 1 - nerve growth factor recetpr

40
Q

Three parts of hair follicles

A

Infundibulum, isthmus, matrical area

41
Q

hair growth period

A

anagen

42
Q

hair growth resting phase

A

telogen

43
Q

hair growth in transition

A

catagen

44
Q

androgenic alopecia

A

pattern baldness - minaturized, finer, lie higher in dermis

Treat with finasteride - block testosterone conversion

45
Q

oil secreting glands

A

sebaceous glands

46
Q

acne caused by 3 things

A

plugging of ostia by hyperkeratootic debris, accumulation of oil, Propionibacterium acnes

47
Q

Eccrine gland is a ___ secretion - without ___ or ____

A

merocrine
apocrine blebbing
holocrine shedding

48
Q

sweating is mediated by ____ of the ANS, triggered via ___

A

sympathetic

Acetylcholine

49
Q

Apocrine secretion is ___, apical portion of secretory cell cytoplasm pinches off and enter lumen

A

decapitation

initially odorless - later contact normal bacterial flora

50
Q

Chromohidrosis is ?

A

colored sweat

51
Q

Apoeccrine glands are ___ sweat glands, found chiefly in the ___

A

hybrid; axilla

cholinergic stimuli - secrete 10x eccrine

DD/BL unit 3 (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions