Intro to derm

Question 1

Skin is the ____ organ

Answer 1

1st largest

Question 2

Skin weighs about ___ kg

Answer 2

4

Question 3

Skin covers __ m2 surface area

Answer 3

2

Question 4

Skin diseases ___% in family practice, ___% in pediatric conditions

Answer 4

8.5; 30

Question 5

Functions of the skin: 7

Answer 5

beauty
barrier (physical, light, immunologic)
vit D syn
Water homeostasis
Thermoregulation
Insulation/Calorie Reservoir
Tough/Sensation

Question 6

Fitzpatrick Skin Type

Answer 6

1-6

red head skin white - black

Question 7

Epidermis is made of a ____ _____ layer

Answer 7

squamous epithelial

Question 8

Dermis contains connective tissue layer including ____ layer and ____ layer

Answer 8

Papillary

Reticular

Question 9

Papillary layer is a ____ connective tissue

Answer 9

loose

dense = reticular

Question 10

Adnexal structures includes:

Answer 10

apocrine glands
Eccrine glands
Hair
Nails
Sebaceous glands

Question 11

Subcutaneous fat composed of ___cytes

Answer 11

adipocytes

Question 12

Thick skin/hairless is found on ___ and ____

Answer 12

palms and soles

Question 13

List the layers in epidermis

Answer 13

stratum corneum
Stratum granulosum
Stratum spinosum
Stratum basalis (germinativum)

Question 14

Keratinocytes form ____ layer; synthesize ___

Answer 14

barrier

keratin

Question 15

keratin is a major _______ of the skin

Answer 15

intracellular fibrous protein

Question 16

Melanocytes side in ___ layer of the epidermis in a __:__ ratio, synthesize ___, which is packaged in granules called ____

Answer 16

basal
1:10 (melanocyte:keratinocyte
Melanin
Melanosomes

Question 17

Langerhand cells are found in ___ epidermal layers, are the ____ cells of epidermis for ______ immune reaction

Answer 17

all
dendritic cells
cell mediated immune reactions (processing/presenting antigens)

Question 18

Eumelanin

Answer 18

Black/brown pigment melanin

Question 19

Pheomelanin

Answer 19

yellow to red/brown pigment

Question 20

Skin color variation of light/dark melanosome distribution

Answer 20

ligh: cluster above nucleus
Dark: individually throughout cytoplasm

Question 21

Stratum basalis = _____ layers

Answer 21

basal cell

Question 22

Stratum basali consists of a single layer of ___ or ___ cells

Answer 22

columnar/cuboidal (keratinocytes)

Question 23

Cell attachment to stratum basalis include

Answer 23

hemidesmosomes (attach basal cells to basal laminal of dermal epidermal junction)
Desmosome: Attach keratinocytes to each other
Tonofilaments: protein structures into dense plque of desmosomes)

Question 24

Stratum Spinosum

Answer 24

synthesis involucrin/membrane coating granules

prickly appeance due to desmosome attach. between cells

Question 25

Stratum Granulosum

Answer 25

Keratohyalin granules contain profilaggrin

Question 26

Filaggrin _________,and is important in barrier function of skin

Answer 26

crosslinkes keratin tonofilaments

Question 27

Stratum lucidum under light microscope, a thin staining band, seen only in ___ skin.

Answer 27

thick

has no nuclei/organelles

Question 28

Papillary layer contains ____ corpuscles

Answer 28

Meissner

Question 29

Reticular Layer has ___ corpuscles

Answer 29

Pacinian

Question 30

Papillary layer contains _________ and pathway for ____ cells

Answer 30

Capillary network

defense

Question 31

Reticular layer contains extensive ___ and ___ to provide strength/flexibility

Answer 31

collagen/elastic

Question 32

Reticular layer is pathway for major blood vessels to facilitate ___

Answer 32

thermoregulation

Question 33

Meissner corpuscle is responsible for :

Answer 33

Delicate touch, in dermal papillae of thick skin

Question 34

Pacinian corpuscle

Answer 34

detect virbation
Dermis of thick/think skin
onion like concentric layers

Question 35

_____ terminates within pacinian corpuscles

Answer 35

single sensory nerve fiber

Question 36

Apocrine glands specialize in ___; begins to function in ___

Answer 36

sweat in axillary, pubic, perianal

puberty

Question 37

Eccrine glands are:

Answer 37

traditioanl sweat glands - distributed over all body

Question 38

Contraction of hair by ____ muscle

Answer 38

arrector pili muscle