Immunohematology

Question 1

ABO antigens are _____

Answer 1

carbohydrates

Question 2

plateles has ____ by RBC does not have -___

Answer 2

MHC (class 1)

Question 3

______ attaches H antigen and A/B antigens

Answer 3

glycosyl transferase

Question 4

H antigen = _____________ chain

Answer 4

“core” basic surgar chain

Question 5

Bombay is because

Answer 5

lack transferase - terminal sugar on H antigen

Question 6

Bombay will type to be

Answer 6

O, but O is foreign

Question 7

Isohemagglutins = definition ?

Answer 7

naturally occurring (antiA/B) by 3-6 mo and class IgM

Question 8

Isohemagglutin = IgX?

Answer 8

M - cannot cross placenta

Question 9

Rh d/D antigens are _____

Answer 9

proteins

Question 10

Rh antibody are IgX?

Answer 10

G

Question 11

RhD- mom with RhD+ baby: treatment

Answer 11

RhoGAM 28 weeks and birth (transplacental bleed) prevent mom from immunized to baby for future baby sake

Question 12

RhD- mom and RhD+ baby (mom is already immunized)…

Answer 12

Baby - jaundice - high bilirubin

RIsk penetrate BBB - basal ganglia damage, cerebral palsy, fetal death

Question 13

Heterophile antibody aka =?

Answer 13

cross reactive antibody

Use for diagnostic tests

Question 14

Transfusion cross match steps

Answer 14

Donner RBC + 1 drop receipent plasma - spin down for red, resuspend for aggregation

Question 15

DAT question answered:

Answer 15

“Ab on cells?”

Question 16

IAT question answered:

Answer 16

“Ab to antigen in plasma?”