Drug antidotes Flashcards

1
Q

Antidote for acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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2
Q

Antidote for salicylates

A

NaHCO3 (alkalinize urine), dialysis

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3
Q

Antidote for amphetamines (basic)

A

Nh4Cl (acidify urine)

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4
Q

Antidote for acetylcholinesterase inhibitors, organophosphates

A

Atropine, pralidoxime

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5
Q

Antidote for antimuscarinic, anticholinergic agents

A

Physostigmine salicylate, control hyperthermia

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6
Q

Antidote for beta blockers

A

Glucagon

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7
Q

Antidote for digitalis

A

Normalize K, Lidocaine, anti-digitalis Fab fragments, Mg2+

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8
Q

Antidote for Iron

A

Deferoxamine, deferasirox

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9
Q

Antidote for lead

A

CaEDTA, dimercaprol, succimer, penicillamine

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10
Q

Antidote for mercury, arsenic, gold

A

Dimercaprol (BAL), succimer

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11
Q

Antidote for copper, arsenic, gold

A

penicillamine

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12
Q

Antidote for cyanide

A

Nitrite +thiosulfate, hydroxocobalamin

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13
Q

Antidote for methemoglobin

A

Methylene blue, vit C

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14
Q

Antidote for carbon monoxide

A

100%, hyperbaric O2

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15
Q

Antidote for methanol, ethylene glycol (antifreeze)

A

Fomepizole > ethanol, dialysis

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16
Q

Antidote for opioids

A

Naloxone/naltrexone

17
Q

Antidote for benzodiazepines

A

Flumazenil

18
Q

Antidote for TCAs

A

NaHCO3 (plasma alkalinization)

19
Q

Antidote for heparin

A

Protamine

20
Q

Antidote for Warfarin

A

Vit K, fresh frozen plasma

21
Q

Antidote for tPA, streptokinase, urokinase

A

Aminocaproic acid

22
Q

Antidote for theophylline

A

beta blocker