Hormonal Alterations

Question 1

• Failure of menses to appear (usually begins 11-15)
• Hypothalmic/pituiarty (low FSH); Hyperandrogenism (low FSH); hypergonadotropic hypogonadism (high FSH)
• Symptoms specific to underlying cause
• FSH, LH, prolactin, T, TSH, T4, hCG

Answer 1

Primary Amenorrhea

Question 2

• Absence of menses for 3 months
• Hypothalmic/pituiarty (low FSH); Hyperandrogenism (low FSH); hypergonadotropic hypogonadism (high FSH)
• FSH, LH, prolactin, T, TSH, T4, hCG
• Tx underlying cause, can use estrogen replacement

Answer 2

Secondary Amenorrhea

Question 3

• Terminal episode of menses (12mos), (48-55yrs)
• Hot flashes, fatigue, insomnia, HA, decreased libido, irritablity, vaginal dryness, increased osteoporosis risk
• FSH, Estradiol
• HRT for short period is ok, but long term=negative cardiovascular risks

Answer 3

Menopause

Question 4

• Female missing part or complete X chromosome
• Short stature (normal GH), primary amenhorrhea, webbed neck, Renal abnormalities, hypogonadism
• Increased FSH and LH
• GH given prior to epiphyseal closure; estrogen/progesterone in adulthood

Answer 4

Turner Syndrome