Thyroid Pharm Flashcards
1
Q
- Competitively blocks response to beta adrenergic stimulation–> decreased HR, myocardial contractility, BP, O2 Demand, and portal flow
- AE: DIzziness, fatigue
- Contra: CHF, Bradycardia
- Do not stop suddenly (block box for MI)
A
Beta Blockers
Propanolol
2
Q
- Inhibits Ca from entering vascular smooth muscle and myocardium–>relaxation of coronary vascular smooth muscle–>dilation
- Interactions: cholchcine
- AE: hepatotoxicty, edema, fatigue
- Contraindications; Heart block, severe hypotension,
A
Claclium Channel Blockers
3
Q
-Inhibits synthesis of thyroid hormone by blocking oxidation of iodine in thyroid
-may affect warfarin
-BLACK BOX: liver injury/failure
-
A
Propylthiouracil (PTU)
4
Q
Synthetic T3&T4
- Interactions: I131
- Contra: Adrenal insufficiency, CV, DM
- Replacement/supplmental therapy in hypothyroid
A
Liotrix
5
Q
Synthetic T4
Palpitations, weight loss, (things like hypterhyroid)
-Black box for weight loss use
Hypothyroid Tx
A
Levothyroxine
6
Q
Inhibits synthesis of TH by blocking oxidation of iodine
Hyperthyroid tx
A
Methimazole
