GI Flashcards
Causes of constipation
- neurogenic disorders
- functional or mechanical conditions
- low-residue diet
- sedentary lifestyle
- opioids, especially codeine
- excessive use of antacids
Major mechanisms of diarrhea
- osmotic diarrhea =
- secretory diarrhea = excessive secretion of fluid and electrolytes d/t endotoxins and exotoxins
- motility diarrhea = increase in peristalsis, food not mixed properly
associated with malabsorption syndromes
Types of abdominal pain
- parietal = local, usually more intense
- visceral = poorly localized, radiating pain, general/diffuse
- referred = visceral pain usually felt at some distance from affected organ
Upper GI bleeding
duodenum, stomach, esophagus
Lower GI bleeding
jejunum, ileum, colon, rectum
Types of acute bleeding
- Hematemesis = vomiting blood
- Hematochezia = bright red bleeding from rectum (also could have “coffee ground” appearance, which indicates older blood from farther up GI
- Melena = black, tarry, sticky, foul smelling stool caused by digestion of blood in GI tract
Occult bleeding
slow, chronic blood loss that is not obvious and results in iron deficiency anemia
Achalasia
- type of dysphagia
- is failure of sphincter to relax
Aspiration
vomit into lungs
Manifestations of Dysphagia
- pain at level of obstruction
- vomiting
- aspiration
- weight loss
Manifestations of GERD
- heartburn
- acid regurgitation
- dysphagia
- chronic cough
- asthma attacks
- mid-epigastric pain within 1 hr of eating
Hiatal hernias (HH)
Types:
- sliding = portion of stomach slides or moves into the thoracic cavity through the esophageal hiatus
- paraesophageal = the greater curvature of the stomach herniates through a secondary opening in the diaphragm, and lies alongside the esophagus
Causes of HH
congenitally short esophagus, trauma, weakening of the diaphragmatic muscles
Manifestations of HH
· Asymptomatic · GERD · Dysphagia · Heartburn · Vomiting · Epigastric pain · Regurgitation · Substrenal pain after eating **major complication will be cut off of blood supply and pain
Manifestations of pyloric obstruction
Both:
· Epigastric pain and fullness
· Nausea
· Succussion splash (splashing sound with stethoscope)
· Vomiting
· With prolonged obstruction will see malnutrition, dehydration, extreme debilitation
Congenital:
· Excessive vomiting
Gastritis
inflammatory disorder of the gastric mucosa; can be acute or chronic and affect the fundus or antrum, or both
Causes of acute and chronic gastritis
Acute:
overuse of alcohol, NSAIDs
Chronic:
H-pylori, alcohol, NSAIDs
Manifestations of gastritis
anorexia fullness N/V epigastric pain bleeding
Peptic ulcer
a break, or ulceration, in the protective mucosal lining of the lower esophagus, stomach or duodenum
Superficial ulcers - won’t see perforation or bleeding
Deep/true ulcers - will see bleeding and perforation
Duodenal ulcers
- most common
- caused by H Pylori; also smoking
- patho: high levels of acid secretion (gastrin and pepsin)
-
Gastric ulcers-
- occurs at antral region of stomach
- patho: primary defect is an increased mucosal permeability to hydrogen ions; but gastric secretion tends to be normal or less than normal
Stress ulcers
- related to severe illness
- occurs in stomach and duodenum
-types:
ischemic (within hrs of trauma, burns, hemorrhage, sepsis)
cushing (develop as result of head/brain injury)
Manifestations of Peptic ulcers
Duodenal: chronic, intermittent pain in epigastric area (more pain when stomach is empty because of increased acid); relieved by food or antacids, hemorrhage or perforation
Gastric: pain frequently occurs after eating d/t normal or low acid level production; anorexia; N/V; weight loss
Stress: bleeding
Dumping syndrome
rapid emptying of hypertonic chyme from the surgically residual stomach into the small intestine 10 to 20 minutes after eating
Alkaline reflux gastritis
stomach inflammation caused by reflux of bile and alkaline pancreatic secretions containing proteolytic enzymes that disrupt the mucosal barrier in the remnant stomach
Afferent loop obstruction
intermittent severe pain and epigastric fullness after eating as result of volvulus, hernia, adhesion, or stenosis of duodenal stump on the proximal side of the gastrojejunostmy
Anemia
d/t absorption issues of B12, folate and iron
Bone and mineral disorders
d/t maladsorption of calcium
Maldigestion
failure of the chemical processes of digestion
Malabsorption
failure of the intestinal mucosa to absorb (transport) digested nutrients
Manifestations of pancreatic insufficiency
- fat maldigestion = fatty stools
- weight loss
- deficiency of fat-soluable vitamins A, D, E, and K
A - nightblindness
D - osteoporosis, bone fractures
K - blood clot problems, bruising
E - neurologic problems
Patho of lactase deficiency
fermentation of lactose by bacteria causes gas and osmotic diarrhea
Bile salt
needed to emulsify and absorb fat