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step 2 > Adverse Drug Reactions > Flashcards

Adverse Drug Reactions Flashcards

1
Q

What is the major side effect of zidovudine?

A

Macrocytic anemia

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2
Q

What are the 2 major side effects of didanosine and stavudine?

A

Neuropathy and pancreatitis

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3
Q

What are the common side effects of Abacavir?

A

Hypersensitivity and Stevens-Johnson

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4
Q

What are the common side effects of protease inhibitors?

A

Hyperlipidemia, hyperglycemia

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5
Q

What is the most common side effects of indinavir?

A

Nephrolithiasis

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6
Q

What is the most common side effect of tenofovir?

A

Renal insufficiency

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7
Q

What are the common side effects of statins?

A

Elevated LFTs and myositis

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8
Q

What are the side effects of niacin?

A

Elevation in glucose and uric acid level, pruritis

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9
Q

What are the side effects of fibric acid derivatives?

A

Increased risk of myositis if combined with statins

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10
Q

What are the common side effects of cholestyramine

A

Flatus and abdominal cramping

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11
Q

What are the adverse effects of calcium channel blockers

A

Edema, constipation and heart block

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12
Q

Who can you not use metformin in? Why?

A

People with renal dysfunction, it causes metabolic acidosis

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13
Q

When can you not use thiazoladinediones (glitazones)

A

CHF patients, causes fluid overload

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14
Q

What are the most common adverse effects of inhaled steroids?

A

Dysphonia and oral candidiasis

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15
Q

What are the adverse effects of theophylline?

A

Cardio and neurotoxicity

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16
Q

What are the adverse effects of Zafirleukast?

A

Hepatotoxicity and Churg Strauss

17
Q

What is the main SE of imipenem

A

Seizures

18
Q

What is the toxicity of rifampin?

A

Red coloration

19
Q

What is the SE of isoniazid?

A

Peripheral neuotoxitiy

20
Q

How do you prevent the side effect of isoniazid?

A

give pyridoxine with it

21
Q

What is the toxicity of pyrazinamide?

A

Hyperuricemia

22
Q

What is the SE of ethambutol?

A

Optic neuritis/color vision disruption

23
Q

What gout treatments can you not use with renal insufficiency?

A

Probenecid, NSAIDs and slfinpyrazone

24
Q

What are the side effects of cochicine?

A

Diarrhea and bone marrow supression

25
Q

What are the side effects of methotrexate?

A

Liver toxicity, bone marrow suppression and pulmonary toxicity

26
Q

What is the major side effect of hydroxychloroquine?

A

Retinal toxicity (follow with dilated eye exams)

27
Q

What are the common side effects of sulfasalazine?

A

Bone marrow toxicity, hemolysis in G6PD deficiency and rash

28
Q

What is the common side effect of doxorubicin?

A

Cardiomyopathy

29
Q

What is the common side effect of vincristine?

A

Neuropathy

30
Q

What is the common side effect of Bleomycin?

A

Lung fibrosis

31
Q

What is the common side effect of cyclophophamide?

A

Hemorrhagic cystitis (give Mesna to prevent)

32
Q

What is the common side effect of cisplatin?

A

renal and ototoxicity

33
Q

What are the most common side effects of interferon?

A

Arthragias, thrombocytopenia, depression and leukopenia

34
Q

What is the common side effect of ribavirin?

A

anemia

35
Q

What is the common side effect of adefovir?

A

Renal dysfunction

step 2 (16 decks)

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