Hemocromatosis Flashcards

1
Q

Como ingresa el hierro al sistema?

A

Ferroso

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2
Q

Como se debe de absorber el hierro?

A

Ferroso

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3
Q

Quien convierte el hierro de la dieta en el hierro ferroso

A

Vitamina C

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4
Q

Cuanto de hierro se absorbe al dia

A

1mg/dia

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5
Q

Que mutacion produce la hemacromatosis?

A

Mutacion de la HFE

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6
Q

Cual es el hierro de almacenamiento?

A

Ferritina

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7
Q

Como se mueve el hierro a la sangre que necesita?

A

Transferrina que necesita APOB

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8
Q

VM del GR

A

120 dias

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9
Q

Cuando se injiera al dia de hierro?

A

10-20mg

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10
Q

Cantidad de hierro por tejido

A

75% hemoglobina

10-20% higado

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11
Q

Que es hemosiderosis?

A

Hierro normal en los tejidos

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12
Q

Mutaciond e HFE

A

C282Y

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13
Q

Que provoca la mutacion HFE

A

Aumenta la abosricion de FE en la mucosa intestinal.

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14
Q

Relacion hombre mujeres de hemocromatosis y por que?

A

9:1 por la menstruacion

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15
Q

Dx de hemocromatosis?

A

Se mide IST (mayor de 45% es dx) y Ferritina (aumentada.

IST: Indice de saturacion

IST: Mayor de 45% - genotipo HFE

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16
Q

Tratamiento de hemocromatosis?

A

Felbotomia

Medidas dieteticas

17
Q

Tratamiento de hemocromatosis en px qque no se puede hacer flebotomia?

A

Quelantes