3rd Semester Pharm Final

Question 1

Zofran (odansetron)

Answer 1

Antiemetic usedto prevent nausea and vomiting after surgery, gastroenteritis, cancer chemo, or radiation therapy

Question 2

Neupogen

Answer 2

Drug for shortening WBC recovery period after chemotherapy, preventing pancytopenia

Question 3

Cyclophosphamide

Answer 3

Alkylating chemotherapy drug used to suppress immune system treating lymphoma, leukemia, etc.

Question 4

Methotrexate

Answer 4

Chemotherapeutic agent and immunosuppressant to treat cancers as well as RA and psoriasis

Question 5

Cyclosporine

Answer 5

Immunosuppressant drug used to prevent organ rejection in patients who have received liver, kidney, or heart transplant

Question 6

5 FU

Answer 6

Antimetabolite chemotherapeutic agent

Question 7

7+3 therapy

Answer 7

Cytabrine and daunorubicin used together for treating AML but should be avoided in cardiac disease

Question 8

Bisphosphonates

Answer 8

Class of drugs that prevent the loss of bone density used to treat osteoporosis and similar diseases

Question 9

Gleevac (imatinib)

Answer 9

Tyrosine kinase used alongside bone marrow transplant for treatment of CML, most common issue is fluid retention

Question 10

Rituximab (rituxan)

Answer 10

Part of R-CHOP formula used to treat certain kidns of cancer such as non hodgekin’s lymphoma and CLL, also immunosuppressant used to treat RA and decrease joint pain and swelling

Question 11

Cimetidine (tagamet)

Answer 11

H2 receptor antagonists that decreases acid secretion and inhibits gastrin for heart burn, stomach ulcers, GERD, ADR’s include antiandrogenic effects

Question 12

Ranitidine (zantac)

Answer 12

H2 receptor antagonist that decreases acid secretion for heart burn, stomach ulcers, GERD, few ADR’s

Question 13

Omeprazole (prilosec)

Answer 13

Proton pump inhibitor that irreversibly binds proton pumps reducing secretion of H+, rebound hypersecretion and headache

Question 14

Misoprostol

Answer 14

Synthetic analogue of prostaglandin used for prevention of gastric ulcers caused by long term NSAID therapy, contraindicated in pregnancy

Question 15

Calcium carbonate (tums)

Answer 15

Simple antacid, adverse effects can result in metabolic alkalosis

Question 16

Bismuth subsalicylate (pepto-bismol)

Answer 16

Treats stomach conditions including diarrhea, gas, heartburn, nausea, and stomach discomfort, belongs to antidiarrheal, adverse effects include black color stool and tinnitus

Question 17

Methylcellulose

Answer 17

Bulk forming agent laxative similar to fiber

Question 18

Docusate

Answer 18

Surfactant to allow water to move into feces for non opioid induced constipation

Question 19

Polyethylene glycol (miralax)

Answer 19

Osmotic laxative

Question 20

Diphenoxylate and atropine(Lomotil)

Answer 20

Man made narcotic for acute diarrhea that abuse potential is lowered by atropine

Question 21

Scopolamine (hyoscine)

Answer 21

Anticholinergic drug that depresses neuronal activity in the inner ear for motion sickness

Question 22

Loperamide (immodium)

Answer 22

Antidiarrheal opioid OTC used to treat diarrhea by suppressinb bowel motility including IBS but does not cross BBB preventing abuse

Question 23

N acetylcysteine

Answer 23

Acetaminophen toxicity antidote

Question 24

Physostigmine

Answer 24

Anticholinergic toxicity antidote

Question 25

Flumazenil

Answer 25

Benzodiazepine toxicity antidote

Question 26

Cholinesterase inhibitors and organophosphate toxicity antidote

Answer 26

Atropine

Question 27

Hydroxocobalamin (deriv of B12)

Answer 27

Cyanide toxicity antidote

Question 28

Metoclopramide (reglan)

Answer 28

can treat gastroparesis in patients with diabetes or GERD as it is a gut motility stimulator and antiemetic, side effect tardive diskinesias permanent if unchecked

Question 29

Terbutaline

Answer 29

Drug to inhibit labor

Question 30

Bromocriptine

Answer 30

Prevents lactation from occurring

Question 31

Clonidine

Answer 31

an alpha agonist antihypertensive and sedative for some tics and such in children

Question 32

Lyrica (pregabalin)

Answer 32

GABA analogue used to treat nerve pain including fibromyalgias and treatment of seizures, risk of abuse in opioid abuse disorder patients

Question 33

Gabapentin (neurontin)

Answer 33

GABA analogue anticonvulsant and nerve pain medication, can treat seizures and pain caused by shingles, risk of abuse in opioid use disorder patients

Question 34

examples of strong opioid agonists (4)

Answer 34

- fentanyl - hydromorphone - methadone - morphine

Question 35

Examples of moderate to strong opioid agonists (3)

Answer 35

- codeine - hydrocodone - oxycodone

Question 36

Dextromethorphan/hydrocodone/codeine

Answer 36

Opioid with minimal analgesic activity but good antitussive activity to be used in anticough meds

Question 37

Bupenorphine (suboxone (+naloxone) or buprenex)

Answer 37

Partial opioid agonist that can be used to prevent withdrawal in opioid use disorder, typically induced and maintained for indeterminate amount of time on medication

Question 38

Naloxone (narcan)

Answer 38

used to reverse respiratory and CNS depression caused by opioid agonists

Question 39

Fentanyl

Answer 39

Opioid painkiller with potency approx 100x that of morphine

Question 40

Meperedine (demerol)

Answer 40

Short term opioid, used for treatment of severe acute pain, short half life and highly irritating but sometimes used for drug induced rigors and shivering analgesia post anesthesic patient

Question 41

Methadone

Answer 41

Opioid PO treatment for chronic nociceptive pain, drug abuse treatment programs for opioid addiction, highly addictive and increases risk of overdose risk if combined with other drugs like heroin, does not provide euphoria but does sedate

Question 42

Oxycodone (percocet)

Answer 42

Semi synthetic derivative of morphine 9.5 more potent than codeine and 1.5x more potent than PO morphine

Question 43

hydrocodone

Answer 43

analgesic activity equivalent to codeine, PO only to relieve pain and suppress cough Most widely prescribed drug in the US,

Question 44

Naltrexone (vivitrol

Answer 44

Pure opioid antagonist used for alcohol and opioid abuse by preventing euphoria (but can precipitate withdrawal and has no effect on craving)

Question 45

Tramadol (ultram)

Answer 45

Non opioid central acting agent, PO agent for treatment of moderate to severe pain