HIV/AIDS Flashcards
1
Q
How can HIV/AIDS be transmitted?
A
- sexual contact (most common)
- before birth or -during delivery, -during breastfeeding
- sharing contaminated needles and syringes
2
Q
What is the pathophysiology of AIDS?
A
- virus gains entry to the cells by attaching to the CD4 receptor and a co-receptor via its envelope glycoproteins
- Once integrated into the cellular DNA the provirus resides in the nucleus of infected cells
- Within a few weeks of infection there is a high level of viral replication
- decline in CD4 T cells
3
Q
What is the presentation of AIDS?
A
- Fever and night sweats
- Weight loss
- Skin rashes
- TB
- diarrhoea
- Infections
4
Q
What are investigations for AIDS?
A
- Serum HIV ELISA
- CD4 Cell count
- Serum viral load
- FBE
- TB test
5
Q
What are DDx for AIDS?
A
- EBV
- CMV
- Influenza
- Secondary syphillis
6
Q
What is treatment for AIDS?
A
-anti-retroviral medicines
