vaccines Flashcards
1
Q
Killed vaccines-bacterin
A
antigenically intact can't replicate unable to induce disease Requires adjuvant inactivated-chemicals often need multiple doses
2
Q
does modified live require adjuvant
A
no, it’s growing and dividing so doesn’t need it
3
Q
Subunit vaccines- toxoid
A
does not contain entire intact organism
specific immunogenic structural antigens
requires adjuvant
4
Q
marker vaccines
A
discriminates between vaccine and exposure titers
differentiating infected from vaccinated animals
needs appropriate diagnostic test
5
Q
what are some manufacturing errors
A
immunosuppression
clinical disease
death
abortion
6
Q
how might a vaccine not work
A
prior passive immunizationh immunosuppressed inadequate vaccine wrong organism given too late
7
Q
Common incorrect administration
A
death of live vaccine
inappropriate route
8
Q
vaccine reactions
A
hypersensitivity
neuro
foreign body reaction
9
Q
heterologous vaccine
A
antigenically related to target agent
no adjuvant required
adapted to different host species
