transplatation immunology

Question 1

isograph

Answer 1

twins

Question 2

allograft

Answer 2

same species

Question 3

xenograft

Answer 3

different species

Question 4

transplant rejection

Answer 4

determined by co-dominant genes
offspring accepts parents
parents don’t accept offspring

Question 5

autograph

Answer 5

graft to itself

Question 6

acute cellular rejection

Answer 6

t cells

Question 7

chronic rejection

Answer 7

persistent antibodies produced

fibrosis

Question 8

hyper acute rejection

Answer 8

hypersensitivity type 2

Question 9

acute rejection

Answer 9

hypersensitivity type 4

Question 10

chronic rejection

Answer 10

hypersensitivity type 3/4

Question 11

prevention and treatment of allograft rejection

Answer 11

reduction of immunogenicity
-elimination of leukocytes
-minimize alloantigenic differences
suppression

Question 12

major cross matching

Answer 12

are there ab in the recipient serum that will recognized the RBCs of the donor

Question 13

Minor cross match

Answer 13

are there Ab in the donor serum that will recognize the recipient’s RBCs

Question 14

Transfusion reactions

Answer 14

recipient antibodies to blood group antigen

Question 15

bone marrow transplant

Answer 15

irradiate

Question 16

graft vs host disease

Answer 16

graft recognizes the entire host as a foreign