3. Virus structure/function Flashcards
1
Q
3 morphological classes of viruses?
A
- Icosahedral
- Filamentous
- Pleomorphic
2
Q
How many sides/faces/facets on an icosahedron?
A
20
3
Q
What is a capsomere?
A
Morphological unit that self-assembles into a capsid
4
Q
Simplest capsid is comprised of ______ subunits/capsomeres
A
60 (Because 20 facets, 1 subunit at each triangular corner = 20*3)
5
Q
NK cells are of lymphocyte lineage but lack what?
A
T and B cell recpetors
6
Q
How do NK cells kill cells?
A
By releasing granzymes which induce apoptosis and perforins which lyse cells
7
Q
What inhibits NK cell activation?
A
MHC I
8
Q
NK cells are part of which immune system? They are related to what?
A
Innate
CTLs
