Intervertebral Disc: Cartilaginous End Plate and Transition Zone Flashcards
What is the cartilage end plate derived from?
the epiphyseal plate
What is the thickest part of the cartilage end plate?
around the periphery
What is the thinnest part of the cartilage end plate?
the central part, over the nucleus pulposus
What part of the vertebral body will the cartilage end plate cover?
the cancellous bone at the top or bottom of the vertebral body
What part of the vertebral body upper and lower surfaces will the cartilage end plate not cover?
the epiphyseal rim
What is the principal type of collagen fiber within the cartilage end plate?
type II collagen fiber
What is the direction of collagen fibers within the cartilage end plate?
collagen fibers are aligned anterior to posterior
What is the attachment site for collagen fibers of the inner lamellae of the annulus fibrosus?
the cartilaginous end plate
What cell type is associated with the cartilage end plate?
chondrocytes
What is the earliest indicator of intervertebral disc pathology or degeneration?
changes in the histology of the cartilage end plate
What part of the intervertebral disc is the growth plate?
the transition zone
What is the area of maximum metabolic activity in the intervertebral disc?
the transition zone
What part of the intervertebral disc will exhibit constant remodeling?
the transition zone
