Powerpoint Boards Qs

Question 1

Normal gradient for venous drainage

Answer 1

30-40mmHg

Question 2

Gold standard for occlusion

Answer 2

Hold line 30cm above pump and should drop at 1cm per minute

Question 3

What venous cannulation is considered total bypass?

Answer 3

Bicaval cannulation: SVC and IVC

Question 4

Ultimate limit to venous drainage

Answer 4

Amount of blood returning from great veins from the body

Question 5

Negative pressure you can not exceed when using VAVD

Answer 5

-60 to -100mmHg

Question 6

What factor has the biggest effect of oxygen movement into blood?

Answer 6

Surface area: greater surface area equals greater rate of diffusion

Question 7

What factor has the biggest affect on CO2 diffusion out of blood?

Answer 7

Volume: more volume equals greater diffusion

Question 8

Does turbulence increase or decrease oxygenation?

Answer 8

Increase

Question 9

How is albumin sterilized?

Answer 9

Cold filtered

Question 10

Values for isotonic solutions

Answer 10

~285-295 mOsm/L

Question 11

Only proven intervention to pacify (wet) tubing

Answer 11

Albumin

Question 12

Optimal urine output on pump

Answer 12

0.5-1cc/kg/hr

Question 13

Factor with greater resistance to oxygen diffusion from alveoli to hemoglobin

Answer 13

Alveolar/capillary membranes

Question 14

Factor with greatest resistance to diffusion from RBC to alveoli

Answer 14

Chemical reaction inside cell

Question 15

Gold standard test for HIT antibody diagnosis

Answer 15

C-SRA (serotonin release assay)

Question 16

Most commonly used therapy for HIT

Answer 16

Argatroban

Question 17

Another name for the Reticuloendothelial system (RES)

Answer 17

Mononuclear phagocyte system (MPS)

Question 18

Mast cell membrane stabilizer given if have Type 1 protamine reaction

Answer 18

Cromolyn sodium

Question 19

Four categories of hypothermia

Answer 19

Mild: 32-35
Moderate: 28-31
Deep: 18-27
Profound:

Question 20

Q10 principle

Answer 20

Reaction rates decrease by 50% for every 10C drop in temperature

Question 21

Q7 principle

Answer 21

Oxygen consumption is decreased by 50% for every 7C drop in temperature

Question 22

Safe circ arrest times at 37, 29, 22, 16, 10C

Answer 22

37: 4-5min
29: 8-10min
22: 16-20min
16: 32-40min
10: 64-80min

Question 23

Drugs given by anesthesia for circ arrest

Answer 23

Thiopental: short acting barbituate
Solumedrol: anti inflammatory, stabilize cell membranes

Question 24

How is albumin sterilized?

Answer 24

It is cold filtered

Question 25

How does digitalis work?

Answer 25

Block Na/K pumps

Ca is then left in cell so force of contraction is increased

Question 26

How do bipyridines work?

Answer 26

Prevent hydrolysis of cAMP

Question 27

Pernicious anemia

Answer 27

Low levels of Vitamin B12

Question 28

How does Hydroxyurea work?

Answer 28

Causes sickle cell hemoglobin to be diluted out by increased production of fetal hemoglobin when used with Epo Alfa

Question 29

Effect of giving Isuprel on bypass

Answer 29

Blood pressure decreases

(Typically, is a positive chronotrope but triggers solely off heart rate so in bypass it’s secondary action is vasodilation)

Question 30

Aminoglycosides contaimdication

Answer 30

Pregnancy: all amino glycosides cross placenta and accumulate in fetus

Three affects: ototoxicity, nephrotic incite, neuromuscular toxicity