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USMLE > Oncogenic Microbes and Carcinogens > Flashcards

Oncogenic Microbes and Carcinogens Flashcards

1
Q

EBV

A

Burkitt lymphoma
Hodgkin lymphoma
Nasopharyngeal carcinoma
CNS lymphoma (in immunocompromised patients)

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2
Q

HBV, HCV

A

Hepatocellular carcinoma

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3
Q

HHV-8 (Kaposi sarcoma-associated herpesvirus)

A

Kaposi sarcoma

Body cavity fluid B-cell lymphoma

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4
Q

HPV

A

Cervical and penile/anal carcinoma (16, 18), head and neck or oral throat cancer

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5
Q

H. pylori

A

Gastric adenocarcinoma and MALT lymphoma

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6
Q

HTLV-1

A

Adult T-cell leukemia/lymphoma

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7
Q

Liver fluke (clonorchis sinesis)

A

Cholangiocarcinoma

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8
Q

Schistosoma haematobium

A

Bladder cancer (squamous cell)

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9
Q

Aflatoxins (Aspergillus)

A

Liver –> hepatocellular carcinoma

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10
Q

Alkylating agents

A

Blood –> leukemia/lymphoma

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11
Q

Aromatic amines (benzidine, 2-naphthylamine)

A

Bladder –> transitional cell carcinoma

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12
Q

Arsenic

A

Liver –> angiosarcoma
Lung –> lung cancer
Skin –> squamous cell carcinoma

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13
Q

Asbestos

A

Lung –> bronchogenic carcinoma > mesothelioma

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14
Q

Carbon tetrachloride

A

Liver –> centrilobular necrosis, fatty change

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15
Q

Cigarette smoke

A

Bladder –> transitional cell carcinoma
Esophagus –> squamous cell carcinoma/adenocarcinoma
Kidney –> renal cell carcinoma
Larynx –> squamous cell carcinoma
Lung –> squamous cell and small cell carcinoma
Pancreas –> pancreatic adenocarcinoma

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16
Q

Ethanol

A

Liver –> hepatocellular carcinoma

17
Q

Ionizing radiation

A

Thyroid –> papillary thyroid carcinoma

18
Q

Nitrosamines (smoked foods)

A

Stomach –> gastric cancer

19
Q

Radon

A

Lung –> lung cancer (2nd leading cause after cigarette smoke)

20
Q

Vinyl chloride

A

Liver –> angiosarcoma

USMLE (38 decks)

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