Neurotransmitters Flashcards

1
Q

Norepinephrine

Anxiety? Depression?

A
Increased = anxiety
Decreased = depression
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2
Q

NE synthesis

A

Locus ceruleus (pons) = stress and panic

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3
Q

Dopamine

Huntington? Parkinson? Depression?

A
Increased = Huntington
Decreased = Parkinson, depression
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4
Q

Dopamine synthesis

A

Ventral tegmentum and Substantia nigra compacta

Midbrain

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5
Q

Serotonin

Parkinson? Anxiety? Depression?

A
Increased = Parkinson
Decreased = anxiety and depression
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6
Q

5HT synthesis

A

Raphe nucleus (pons, medulla, midbrain)

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7
Q

ACh

Parkinson? Alzheimer? Huntington?

A
Increased = Parkinson
Decreased = Alzheimer, Huntington
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8
Q

ACh synthesis

A

Basal nucleus of Meynert

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9
Q

GABA

Anxiety? Huntington?

A

Decreased = anxiety, Huntington

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10
Q

GABA synthesis

A

Nucleus accumbens (reward center, pleasure, addiction, fear)

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11
Q

Changes in anxiety

A
Increased = NE
Decreased = 5HT, GABA
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12
Q

Changes in depression

A

Decreased = NE, dopamine, 5HT

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13
Q

Changes in Huntington

A
Increased = dopamine
Decreased = ACh, GABA
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14
Q

Changes in Parkinson

A
Increased = 5HT, ACh
Decreased = dopamine
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15
Q

Changes in Alzheimer

A

Decreased = ACh

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16
Q

Locus ceruleus (pons)

A

Norepinephrine

17
Q

Ventral tegmentum and SNc (midbrain))

A

Dopamine

18
Q

Raphe nucleus (pons, medulla, midbrain)

A

5HT

19
Q

Basal nucleus of Meynert

A

ACh

20
Q

Nucleus accumbens

A

GABA