Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Correlate Review > Flashcards

Correlate Review Flashcards

1
Q

Sildenafil (viagra) and antibiotics

A

Viagra is metabolized by CYP450 so use the smallest dose possible when using with other 3A4 drugs (macrolides except azithro and azoles).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Step 4 Asthma Treatment

A

Medium Dose ICs and LABA or montelukast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Step 2 Asthma Treatment

A

Low Dose ICS or cromolyn or montelukast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

H. Pylori Treatment

A

Clarithromycin (caution with statins). PPIs can cause false positives.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Betaxolol

A

Second Gen Beta-Blocker (Cardioselective)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

First Gen Beta-Blocker (Non-Cardioselective) Side Effects

A

Bronchospasm, worsen CHF, exercise intolerance, depression, fatigue, raise lipids, imparied glucose tolerance, decreased libido. Avoid abrupt withdrawal.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Intermittent Asthma

A

less than or equal to 2 times a week. No nighttime awakenings.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Parkinson’s and DA

A

Smooth movement. Substantia nigra to basal ganglia .

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Furosemide and metoprolol and lisinopril

A

All lower BP (hypotension). Decreased renal blood flow with increase digoxin levels.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Stage 1 HTN

A

140-159/90-99

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Fexofenadine (Allegra)

A

Second Generation H1 blocker. Longer lasting and non sedating. Approved for pilots.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Step 1 Asthma Treatment

A

SABA PRN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Prochlorperazine (compazine)

A

Anti-emetic. Has anticholinergic effects, CNS depression EPS.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Ranitidine (Zantac)

A

H2 blocker. Used as adjunct for uticaria.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Citalopram (celexa) Side Effects

A

Insomnia, somnolence, nausea, dry mouth, sexual dysfunction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Velafaxine (Effexor) indications

A

SNRI. MDD, GAD, SAD, panic.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Aliskren (tekturna) Side Effects

A

Hyperkalemia, renal impairment, hypersensitivity. Contraindicated in pregnancy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Diphenhydramine (Benadryl)

A

(Nytol, Sominex). First Generation H1 blocker.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

African Americans and HTN

A

CCB or thiazide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Salmerterol/fluticasone

A

LABA + ICS. Control. Thrush and hoarseness.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Labetolol

A

Combined Alpha and Beta antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Meclizine (Antivert)

A

First Generation H1 blocker.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Hydrocodone Schedule

A

Schedule II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

IBD Treatment

A

Newly diagnosed cases should get a tapering dose of prednisone. adalimumab (humira), infliximab (remicade).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Drugs that potentiate Digoxin

A

Diuretics (except spironolactone), Propranolol, amiodarone, Antibiotics (erythromycin and tetracycline), IV calcium, CCB, quinidine, thyroid hormone.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Hyperthyroidism and HTN

A

BB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Norepinephrine in the cerebral cortex

A

Arousal and attention

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Nociceptive Pain Treatment

A

NSAIDs, Tramadol, opiates, muslce relaxants, PT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Step 6 Asthma Treatment

A

Add oral Glucocorticoid.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Metoprolol

A

Second Gen Beta-Blocker (Cardioselective)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Spironolactone

A

potassium sparing diuretic and aldosterone antagonsit (decreases number of sodium channels).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Norepinephrine in the hypothalamus

A

Appetite. Increased NE suppresses appetite.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Stage C COPD Treatment

A

ICS + LABA or LAMA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Morphine Schedule

A

Schedule II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Acebutolol

A

Second Gen Beta-Blocker (Cardioselective)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Norepinephrine targets

A

Limbic lobe, Cerebral Cortex and hypothalamus.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Contraindicated in Depression

A

BB, central alpha blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Stage D COPD Treatment

A

ICS+ LABA + LAMA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Metoclopramide (reglan)

A

Prokinetic. Risk of EPS and tardive. SE: cramping and diarrhea.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Norepinephrine in the limbic lobe

A

Mood. Increased/decreased NE release is associated with bipolar disorder.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Prazosin (“-zosins”) Side Effects

A

First dose phenomenon (postural hypotension). fatigue, weakness, nasal congestion and HA. Beneficiall effect on lipids and BPH.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Bisacodyl (dulcolac)

A

Stimulant laxative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Essential tremor and HTN

A

BB (nonselctive)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Timolol

A

First Gen Beta-Blocker. Non-Cardioselective.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

Citalopram (celexa) Indications

A

SSRI. MDD only

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

CKD and HTN

A

ACEI/ARB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

Clorpheniramine (Chlor-trimeton)

A

First Generation H1 blocker.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

Risks of PPIs

A

Malabsorption (ca, mg, iron, b12), osteoporosis, respiratory/enteric infections, CKD.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

Serotonin in the cerebral cortex

A

Sensation and perception

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

SSRI/SNRI Black Box Warning

A

Incrased suicidal thinking in children and young adults (monitor closely during first 1-2 months). Trip a manic episode if underlying bipolar disorder. Must taper down gradually.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

Dicyclomine

A

Anti-spasmodic used for IBS. Anticholinergic properties. Caution in elderly.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

Combined Alpha and Beta antagonist Side effects

A

Orthostatic hypotension, bronchospasm. Really only used in HTN emergencies or after an MI.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

NSAIDS and Renal Function

A

NSAIDS cause vasoconstriction of the afferent arterioles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

Sertraline (Zoloft) Indications

A

SSRI. MDD, OCD, Panic, PTSD, SAD, nocturnal eating, PMDD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

Norepinephrine production site

A

Brianstem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

Propranolol

A

First Gen Beta-Blocker. Non-Cardioselective.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

Contraindicated in gout

A

diuretics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

Neuropathic Pain Treatment

A

Neurontin (gabapentin), Lyrica (pregabalin), Elavil (amitriptyline), Cymbalta (duloxetine), lidoderm patch, spinal cord stimulator, ESI.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

Magnesium antacids Side effects

A

Diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

Antihistamines and Breast Feeding

A

Loratadine (Claritin) and Cetirizine (Zyrtec)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

Contraindicated in second or third degree block

A

BB, verampamil/diltiazem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q

Sodium-bicard Side effects

A

Fluid retention (caution in CHF)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q

Pre-HTN

A

120-139/80-89

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q

Chronic Stable Angina

A

BB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
65
Q

Clonidine and Methyldopa MOA

A

Central acting alpha agonist (alpha2). Reduces SNS vasoconstriction and vascular resistance.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
66
Q

Statins and antibiotics

A

Risk of elevated transaminase levels, myopathy, rhabdomyolysis and ARF. Contraindicated with Erythromycin, itraconazole, niacin and gemfibrozil.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
67
Q

Desvenlafaxine (pristiq) Indications

A

SNRI. MDD only.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
68
Q

Stage 2 HTN

A

greater than 160/100

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
69
Q

Fluoxetine (Prozac) Side Effects

A

Insomnia (take in am), HA, Nervousness, decreased libido, diarrhea, anorexia. Longest half life with the broadest effects, least specific for 5HT.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
70
Q

Oral Gluccocotricoids and asthma

A

Prednisone. Used for acute exacerbations. SE: anxiety, agitation, insomnia, increased appetite.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
71
Q

ARB (“-sartans”) MOA

A

Blocks the effect of angiotensin II on the tissue.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
72
Q

Urticaria treatment

A

Second generation antihistamines with an H2 blocker as adjunct. Consider adding a tapering course of steroids.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
73
Q

Opiates and ESRD

A

DOC is fentanyl. Avoid morphine, demerol, vicodin, codeine.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
74
Q

Docusate (colace)

A

Stool Softener. Safe in pregnancy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
75
Q

Nifedipine (“-pines”) MOA

A

CCB. Dihydropyridines that cause arteriolar smooth muscle relaxation and decrease peripheral resistance. Potent vasodilators.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
76
Q

Olopatadine (patanol)

A

Antihistamine eye drops. Mast cell stabilizer.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
77
Q

A-Fib and HTN

A

BB, verapamil/diltiazem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
78
Q

Escitalopram (lesapro) Side Effects

A

Insomnia, somnolence, nausea, ejaculation disorders.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
79
Q

Buproprion (wellbutrin) Side Effects

A

Insomnia, HA, nausea, weight loss, dry mouth, tachycardia, dizziness. Less Sexual side effects compared to SSRIs. Avoid in patients with seizure disorder (lowers the seizure threshold) and anorexia.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
80
Q

ARB (“-sartans”) Side Effects

A

hypotension and hyperkalemia. Contraindicated in pregnancy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
81
Q

Aliskren (tekturna) MOA

A

Direct renin inhibitor. Decreases plasma renin activity.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
82
Q

Antihistamine Side Effects

A

Anticholinergic side effects (First generation more so than second). Sedation (First gen). Impotence, urinary hesitancy, sedation, confusion, weight gain, hypersensitivity, prolonged QT (arrhythmias).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
83
Q

Montelukast (singulair)

A

Leukotriene receptor antagonist. SE: URIs, HA, abdominal pain, mood changes.

84
Q

Thiazide MOA

A

Block sodium reabsorption in the distal convoluted tubule via Na/Cl transporter.

85
Q

Contraindicated in Liver Disease

A

Methyldopa

86
Q

Levaquin Renal dosing (CAP)

A

Renal dosing is based on the creatinine clearance. Monitor serum levels of the drug.

87
Q

Step 3 Asthma Treatment

A

Medium Dose ICS

88
Q

Sertraline (Zoloft) Side Effects

A

Insomnia, HA, Dizziness, fatigue, Decreased libido, somnolence, nausea, diarrhea, anorexia, dry mouth

89
Q

Antiepileptics and antibiotics

A

such as phenytoin, carbamazepine and phenobarbital. Effects are ptentiated by inhibitors of CYP450: Macrolides (EXCEPT Azithromycin), and the azoles.

90
Q

Serotonin in the hypothalamus

A

Appetite and sleep

91
Q

Second Gen Beta-Blocker (Cardioselective) Side Effects

A

Less side effects than first generation. Still raise lipids. Avoid abrupt withdrawal (MI, rebound HTN, bronchoconstriction).

92
Q

Infective Esophagitis

A

Fluconazole. Beware of interaction with statins (rhabdo and myopathy).

93
Q

Codeine Schedule

A

Schedule II

94
Q

Buproprion (wellbutrin) Indications

A

DA reuptake inhibitor. MDD, SAD and smoking cessation. Can be used in combination with SSRIs.

95
Q

MDD treatment plan

A

Antidepressants (SSRIs are first line), +/- psychotherapy, follow up in 1-2 weeks (SE profile), instructions on when to contact provider, crisis line number, community resources. Refer if PHQ-9 is greater than 16.

96
Q

Nadolol

A

First Gen Beta-Blocker. Non-Cardioselective.

97
Q

Dopamine Production to Targets

A

Substantia nigra to basal ganglia Ventral tegmentum to nucleus accumbens/frontal cortex

98
Q

SSRI/SNRI Patient Education

A

Takes 2-8 weeks to have effect. Side effects usually occur during the first few days and resolve in a week. Do not stop abruptly (need taper).

99
Q

Severe asthma

A

Throughout the day. Night time awakenings weekly.

100
Q

Ondansetron (zofran)

A

Anti-emetic. QT prolongation and risk of serotonin syndrome.

101
Q

Misoprostol (cytotc)

A

Prevents ulceration induced by NSAIDs. Contraindicated in pregnancy.

102
Q

Contraindicated in Renovascular Disease

A

ACEI/ARB, renin inhibitor

103
Q

OCPs and antibiotics

A

Insufficient evidence but still encouraged to use an alternative form of birth control.

104
Q

ACEI (“-prils”) Side Effects

A

Dry cough, orthostatic hypotension, hyperkalemia, angioedema, elevated creatinine, rash. Contraindicated in Pregnancy.

105
Q

Angina and HTN

A

BB or CCB

106
Q

Desvenlafaxine (pristiq) Side Effects

A

Same as SSRIs with adrenergic effects. Insomnia, HA, nervousness, diaphoresis, constipation/diarrhea, dizziness, increased BP, ejaculation/orgasm difficulties.

107
Q

Parozetine (Paxil) Side Effects

A

Most weight gain of all SSRIs (especially in combo with antipsychotic). Insomnia, HA, Dizziness, fatigue, Decreased libido, somnolence, nausea, diarrhea, anorexia, dry mouth

108
Q

Mild Asthma

A

more than twice a week

109
Q

Migraines and HTN

A

BB

110
Q

Contraindicated in hyponatremia

A

thiazides

111
Q

Stage A COPD Treatment

A

SABA or SAMA PRN

112
Q

Mitrazapine (Remeron) Side Effects

A

Somnolence, increased appetite, weight gain, increased cholesterol, constipation, dry mouth. Less sexual side effects than SSRIs.

113
Q

Dilitiazem MOA

A

Middle ground between the dipines and verapamil.

114
Q

Tylenol with Codeine Schedule

A

Schedule III

115
Q

Oxymorphone Schedule

A

Schedule II

116
Q

Contraindicated in Pregnancy

A

ACEI/ARB, renin inhibitor

117
Q

Verapamil and Diltiazem Indications

A

Arrhythmias, variant angina, long term angina and a-fib.

118
Q

Famotidine (Pepcid)

A

H2 blocker. Used as adjunct for uticaria.

119
Q

Promethazine (Phenergan)

A

First Generation H1 blocker.

120
Q

ACEI (“-prils”) MOA

A

Block the enzyme to stop the formation of angiotensin II. Causes venous dilation (decreases resistance and BP)

121
Q

Anticholinergics and COPD

A

Relief. Long acting: Tiotripium (spiriva). Short acting: Ipatripium (atrovent). Dry mouth, cough, HA, nausea, blurred vision, dizziness.

122
Q

Pindolol

A

First Gen Beta-Blocker. Non-Cardioselective.

123
Q

ACEI/ARBs and Renal Function

A

Vasodilate the efferent arterioles. Increase the risk or hyperkalemia with renal failure.

124
Q

Loops Side Effects

A

HYPOKALEMIA.

125
Q

Duloxetine (cymbalta) Side Effects

A

Insomnia, somnolence HA, Dizziness, fatigue, nausea, anorexia, dry mouth, contstipation/diarrhea, sexual dysfunction. Doesn’t increase BP like other SNRIs. Contraindicated in liver disease.

126
Q

Scabies Antihistamine Choice

A

Hydroxyzine (Atarax) stops the itching and helps with sleep. Treatment also includes permethrin cream 5%.

127
Q

Drugs that Cause Constipation

A

Anti-psychotics, aluminum hydroxide, dicyclomine (bentyl), antidepressants, CCBs, calcium, opiods.

128
Q

Second Gen Beta-Blocker (Cardioselective) Indications

A

Good to treat HTN if previous MI, Stable CHF, angina or A-fib

129
Q

Nociceptive Pain

A

Injury to tissues. Somatic or visceral.

130
Q

Ketotifen (zatidor)

A

Antihistamine eye drops. Mast cell stabilizer.

131
Q

Potassium sparing Diuretics Side Effects

A

Don’t combine with ACEI/ARBs due to risk of hyperkalemia. Not great diuretics, may be combined with loops to balance potassium effects.

132
Q

Albuterol

A

Short acting beta agonist. SE: tachycardia, tremor, nervousness, dizziness.

133
Q

Triamterene

A

potassium sparing diuretic. Inhibits Na/K exchanger in the collecting tubule independent of aldosterone.

134
Q

Magnesium Hydroxide

A

Osmotic Laxative

135
Q

NSAIDS and ACEI/ARB and Diuretics

A

BAD NEWS. Increased risk of AKI.

136
Q

H2 blockers Indications

A

Quick onset for on-demand relief. Most effective at decreasing night time acid production.

137
Q

Azelastine (Optivar)

A

Antihistamine eye drops

138
Q

Mitrazapine (Remeron) Indications

A

Presynaptic alpha 2 antagonist (enhances noradrenergic and serotonergic transmission). Often used in elderly patients with depression, sleep, and increased appetite.

139
Q

Verapamil and Diltiazem Side Effects

A

Diarrhea (verapamil). Bradycardia, SA node dysfunction, heart block.

140
Q

BPH and HTN

A

Alpha blocker (zosins)

141
Q

Moderate asthma

A

Daily

142
Q

Thiazide Side Effects

A

hypokalemia, hyperuricemia, hyponatremia, hypercalcemia, hypertriglyceridemia, hypercholesteremia.

143
Q

Post MI and HTN

A

ACEI/ARB, BB, Adlo agonist

144
Q

Bisoprolol

A

Second Gen Beta-Blocker (Cardioselective)

145
Q

Loratadine (Claritin)

A

Second Generation H1 blocker. Longer lasting and non sedating. Approved for pilots and breast feeding (category B).

146
Q

Cetririzine (Zyrtec)

A

Second Generation H1 blocker. Longer lasting and non sedating (Most sedation of second gen). Ok for breast feeding (category B).

147
Q

Loop Diuretics

A

Furosemide, torsemide, bumetanide

148
Q

Methadone Schedule

A

Schedule II

149
Q

Serotonin in the Limbic Lobe

A

Mood. Decreased serotonin release is correlated to mood disorders and OCD

150
Q

Acute COPD exacerbation treatment

A

Albuterol/ipratropium (duoned) SVN, intensify SABA +/- SAMA, Oral steroids, Antibiotics (macrolide or fluoroquinolone) if 2/3 of the cardinal symptoms (dyspnea, sputum volume, purulent sputum).

151
Q

MDD Treatment length

A

at least 4-9 months after determining therapeutic dose. Risk of reoccurence should have 1-3 years of treatment. Multiple episodes or comorbid disorders will have indefinite treatment.

152
Q

Carvediolol

A

Combined Alpha and Beta antagonist

153
Q

Fluoxetine (Prozac) Indications

A

SSRI. MDD, OCD, Bulemia, panic, PMDD, depression with bipolar disorder (combined with olanzapine (zyprexa)).

154
Q

Diluadid Schedule

A

Schedule II

155
Q

Addiction pathaway

A

Pleasure and reward. DA from Ventral tegmentum to nucleus accumbens/frontal cortex.

156
Q

Metformin and Renal Function

A

Contraindicated in ARF due to the high risk of lactic acidosis.

157
Q

Clonidine and Methyldopa Side Effects

A

Orthostatic hypotension, sedation, drowsiness, avoid abrupt withdrawal (rebound HTN). Used only for refractory HTN.

158
Q

Verapamil MOA

A

CCB. Diphenylalkylamines. Less vasodilation. Has negative ionotripic and chronotropic properties.

159
Q

Azelastine + fluticasone (Dymista)

A

Antihistamine nasal spray

160
Q

Antihistamine Contraindications

A

BPH and glaucoma (closed angle).

161
Q

Serotonin Targets

A

Limbic Lobe, Hypothalamus, cerebral cortex.

162
Q

Parozetine (Paxil) Indications

A

SSRI. MDD, Panic, OCD, GAD, PTSD, SAD, PMDD

163
Q

Step 5 Asthma Treatment

A

High Dose ICS and LABA or montelukast

164
Q

Thiazide Diuretics

A

HCTZ, Chlorothiazide, Metolazone. First line choice for african americans.

165
Q

Duloxetine (cymbalta) Indications

A

SNRI. MDD. neuropathic pain (DM) and fibrimyalgia.

166
Q

Anaphylaxis Treatment

A

Epinephrine! Diphenhydramine (benadryl). IM glucocorticoid (dexamethasone). Famotidine (pepcid).

167
Q

Amiloride

A

potassium sparing diuretic. Inhibits Na/K exchanger in the collecting tubule independent of aldosterone.

168
Q

Osteoporosis and HTN

A

Thiazides

169
Q

Serotonin Production Site

A

Brainstem

170
Q

Contraindicated in Angioedema

A

ACEI

171
Q

Cimetidine

A

H2 blocker. CYP450 and antiandrogen effects.

172
Q

Escitalopram (lesapro) Indications

A

SSRI. MDD and GAD.

173
Q

HTN Treatment Goals

A

140/90 unless older than 60 (without CKD or DM) then 150-90.

174
Q

Ceftriaxone renal dosing (CAP)

A

No adjustment needed

175
Q

Nifedipine (“-pines”) Side Effects

A

reflex tachycardia, HA, flushing (short term). Edema. Less affect on contractility.

176
Q

Systolic Failure and HTN

A

ACEI/ARB, BB, Diuretic, aldosterone agonists.

177
Q

Stage B COPD Treatment

A

LAMA or LABA

178
Q

Atenolol

A

Second Gen Beta-Blocker (Cardioselective)

179
Q

PPI indications

A

Reflex esophagitus. Takes 3-4 days to work. Take every morning before breakfast. Caution of rebound effect.

180
Q

Ocycodone Schedule

A

ScheduleII

181
Q

PUD Treatment

A

PPI, amoxicillin and clarithromycin. Can add bismuth subsalicylate.

182
Q

Fentanyl Schedule

A

Schedule II

183
Q

Azelastine (Astelin)

A

Antihistamine nasal spray

184
Q

Digoxin and metoprolol interaction

A

Both cause bradycardia which can lead to an AV block

185
Q

Digoxin and Furosemide Interaction

A

Loop diuretics can cause hypokalemia which increases digoxin toxicity.

186
Q

Velafaxine (Effexor) Side Effects

A

Same as SSRIs with adrenergic effects. Insomnia, HA, nervousness, diaphoresis, constipation/diarrhea, dizziness, increased BP, ejaculation/orgasm difficulties. Take with food. Must be tapered (impending sense of doom).

187
Q

Contraindicated in hyperkalemia

A

Aldo antagonists, ACEI/ARB, renin inhibitor

188
Q

DOC for Reflux esophagitus

A

PPIs (prazoles).

189
Q

Vasospastic Angina DOC

A

CCB

190
Q

Contraindicated in Bronchospastic Disease

A

BB

191
Q

Naphazoling (naphcon A)

A

Antihistamine eye drops

192
Q

Fluticasone (flovent)

A

low dose ICS

193
Q

Promethazine (phenergan)

A

Anti-emetic. SE: Sedation, CNS/Respiratory depression. Contraindicated in children less than 2 due to respiratory depression.

194
Q

Soma Schedule

A

Schedule IV

195
Q

MDD Screening

A

PHQ-9. 5-9 (minor), 10-14 (moderate), 15-19 (mod-severe), 20 or more (severe).

196
Q

Warfarin and Antibiotics

A

Ciprofloxacin, macrolides (erythromycin, azithromycin), metronidazole, bactrim are contraindicated. Almost all antibiotics can potentiate warfarin but inhibiting the intestinal flora that produces vitamin K.

197
Q

Azithromycin Renal dosing (CAP)

A

No adjustment needed

198
Q

Dimenhydrinate (Dramamine)

A

First Generation H1 blocker.

199
Q

Loop MOA

A

Blocks Na/K/2Cl transporters in the thick ascending limb.

200
Q

Fluoroquinolones (floxacins)

A

Don’t combine with cations (ca, mg, al, iron). Will reduce the absorption of fluoroquinolones. At least take 2-4 hours apart.

201
Q

MDD DSM-V Criteria

A

Five or more symptoms (SIGECAPS) for at least 2 weeks. At least one symptom must be depressed mood or lost of interest/pleasure.

202
Q

MDD Presentation

A

SIGECAPS. Sleep, Interest (lack), Guilt, Energy (decreased), Concentration (indecisiveness), Appetite, Psychomotor (agitation or retardation), Suicidal ideation.

203
Q

Poison Ivy Treatment

A

Steroid cream (triamcinolone) and Second gen antihistamine (zyrtec). Steroid taper if not improving.

204
Q

Raynaud’s and HTN

A

CCB (dipines)

205
Q

Penbutolol

A

First Gen Beta-Blocker. Non-Cardioselective.

206
Q

Prazosin (“-zosins”) MOA

A

Alpha antagonist. Reduces NE constriction leading to vasodialtion.

207
Q

Hydroxyzine (Atarax)

A

(vistaril) First Generation H1 blocker. Extremely sedating.

Pharmacology (24 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions