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Pharma Oral > 58. Macrocyclic lactones > Flashcards

58. Macrocyclic lactones Flashcards

1
Q

Avermectins

A 
Iver-
Dora-
Aba-
Sela-
-Mectin
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2
Q

Milbemycins

A

Moxidectin

Milbemycin oxide

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3
Q

Moa

A

Gaba-ergic
> potentiate inhibitory transmitters
> binding nerve cell receptors in nematodes + arthropods
> Ca+ influx

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4
Q

Spectrum

A

Flea, lice, mange mite, larvae, ticks, demodox

Antihelmintic spectrum: Nematodes: heartworm

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5
Q

SI

A

Abamectin + moxidectin NOT calves under 4 months
CNS depression
NS signs: collies

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6
Q

Application:

A

SC: ru, sus
Po: moxidectin (eq paste), ivermectin
Dermal (spot on): Ivermectin, moxidectin
-selamectin, moxidectin, milbemycin oxime: dogs

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Pharma Oral (12 decks)

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