Pathology Flashcards
Charcot-Bouchar aneurysm associated with? location? result of rupture? symptoms?
associated with: htn
locations: basal ganglia; cerebellum; thalamus; pons
result: INTRAcerebral hemorrhage (<1mm)
symptoms: progressive neurological deficits; headache may follow
Saccular (berry) aneurysm associated with? Locations? result of rupture? symptoms
associated with: ADPKD; ehlers danlos; HTN
location: circle of willis
result: subarachnoid hemorrhage (2-25mm)
symptoms: sudden severe hemorrhage / focal neuro deficits
which vitamin deficiency mimics freidrichs ataxia (ar)
vit E
mimics
Signs and symptoms of friedricks ataxia?
hypertrophic cardiomyopathy
kyphoscoliosis
arched feet?
ataxia - degeneration fo spinocerebellar tracts
hyporeflexia - peripheral nerve degeneration
loss of position / vibration sense - dorsal columns
signs of thiamine deficiency
high cardiac output failure (dilated cardiomyopathy)
peripheral neuropathy
Wernicke’s encephalopathy - ataxia / confusion / opthalmoplegia
- damage to mamillary bodies
special growth medium for fungi
sabouraud
Whipples disease
foamy macrophages in lamina propria
diarrhea
neuro/cardiac/arthralgia
Tropheryma whippeli - PAS+ and diastase resistant
Meconium ileus think?
Cystic fibrosis - all full term infants
Hirschprungs disease
aganglionic rectum at the transition zone lead to rectosigmoid menocium - seen often in downs
Blown pupil?
Uncle herniation
effects oculomotor nerve - fixed dilated pupil with down and out gaze
A transtentorial herniation - i.e. uncal herniation, is most likely to impinge on which nerve and which artery
oculomotor nerve - III - blown pupil (fixed and dilated) with down and out
Posterior cerebral arter –> contralateral homonymous hemiopsnia with macular sparing
*compression of contralateral cerebral peduncle - white tracts - may lead to ipsilateral hemiparesis
histology of celiac intestine
increased intraepithelial lymphocytes with crypt hyperplasia
