6: Microbiology of genital tract infections Flashcards Preview

Reproduction Week 1 2018/19 > 6: Microbiology of genital tract infections > Flashcards

Flashcards in 6: Microbiology of genital tract infections Deck (51)
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1

Gonorrhoea produces a ___ discharge.

Chlamydia produces a ___ discharge.

gonorrhoea - purulent

chlamydia - watery

2

The normal vaginal pH is (acidic / basic).

acidic

3

Which commensal bacteria is most commonly found in the vagina?

Lactobacillus

4

Apart from Lactobacillus, what other organisms are found naturally found in the vagina?

Group B Strep

Candida

Strep viridans

5

Which fungal infection commonly affects the female genital tract?

Candida albicans

6

Non-albicans Candida infections are more common in ____ patients.

immunosuppressed

7

Poorly controlled ___ is a risk factor for Candida infection.

diabetes

8

What is the presentation of Candida infection?

White vaginal discharge

Itch

9

How is candida infection investigated?

Vaginal swab for culture

10

Which antifungal is used for Candida infection?

Clotrimazole

11

What causes bacterial vaginosis?

?Lack of balance

12

What is the presentation of bacterial vaginosis?

Intensely smelly, frothy vaginal discharge

13

In bacterial vaginalis, the normal vaginal bacteria are replaced with which bacteria?

Gardnerella vaginalis

and anaerobes

14

What happens to the vaginal pH in bacterial vaginosis?

Becomes alkaline

i.e the pH increases

15

Bacterial vaginosis is an imbalance of bacteria, not an infection.

Why is it treated regardless?

Risk of genital tract infection

16

Which antibiotic, effective against anaerobes, is effective for treating bacterial vaginosis?

Metronidazole

17

STIs tend to ___.

co-exist

so you test for all of them

18

What is the most common STI in the UK?

Chlamydia trachomatis

19

Chlamydia trachomatis can be split into subtypes depending on its ___.

serology

what it produces

20

How does Chlamydia appear on a Gram stain?

Doesn't stain

21

Which serovars of chlamydia trachomatis cause genital tract infections?

D-K

22

The guidance for antibiotic treatment of chlamydia trachomatis has just changed.

What is the empirical treatment?

Doxycycline 100mg BD for 7 days

23

Before it became doxycycline 100mg, what was the antibiotic treatment for chlamydia?

Azithromycin 1g

24

What are the investigations for genital chlamydia and gonorrhoea in

a) males

b) females?

a) First pass urine sample

b) Vulvo-vaginal swab

25

What other investigations, apart from genital ones, exist for chlamydia and gonorrhoea?

Rectal swab

Throat swab

Eye swab

26

What is the appearance of gonorrhoea on a Gram stain?

Gram -ve intracellular diplococcus

27

What does neisseria gonorrhoeae look like on microscopy?

Gram negative diplococcus

"Two kidney beans facing one another"

28

What type of media is used to culture neisseria gonorrhoeae?

Selective media

kills competitors

29

The samples obtained from first pass urine samples or vulvovaginal swabs are sent for which type of testing?

Nucleic acid amplification tests (NAATs)

More sensitive for diagnosing chlamydia/gonorrhoea than culture

30

Which antibiotic is given for gonorrhoea infection?

Ceftriaxone