8: Male infertility Flashcards Preview

Reproduction Week 1 2018/19 > 8: Male infertility > Flashcards

Flashcards in 8: Male infertility Deck (39)
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1

What area of the embryo has the potential to develop into male or female gonads?

Bipotential gonad ridge

2

Which named ducts develop into the genital tract in

a) males

b) females?

a) Wolffian duct

b) Mullerian duct

3

Which hormone is produced by the testes and encourages development of the male genital tract?

Testosterone

4

Which genital tract develops in the absence of testosterone?

Female genital tract

5

The presence of a Y chromosome causes the development of the ___ genital tract.

male

6

The absence of a Y chromosome causes the development of the ___ genital tract.

female genital tract

XX OR XO

7

congenital insensitivity to androgens i.e testosterone causes what presentation?

Male with external female genitalia but no uterus or ovaries

Often brought up as female until puberty

8

There is a fold of ___ around the scrotum.

What disease can develop from this?

peritoneum

hydrocele

9

Where do the testes develop?

Abdominal cavity

10

Which muscles contract to lift the scrotum in cold temperatures?

Dartos / cremasteric muscle

11

What is another name for undescended testes?

Cryptorchidism

12

Having undescended testes increases a patient's chances of developing which disease?

Sperm cell cancer

13

Within the testes, which cells

a) produce testosterone

b) support sperm cells?

a) Leydig cells

b) Sertoli cells

14

Describe the production of FSH and LH by the anterior pituitary in

a) females

b) males?

a) Cyclical

b) Constant

15

Which hormone is released in a pulsatile manner by the hypothalamus?

GnRH

16

Which hormone triggers spermatogenesis in men?

FSH

17

Which hormone triggers testosterone secretion by Leydig cells?

LH

18

Which hormone is released by Leydig cells and stimulates spermatogenesis?

Testosterone

19

Which enzymes do sperm cells use to digest the zona pellucida of an egg?

Acrosomes

20

Which reaction stops multiple fertilisations of an egg cell?

Zonal reaction

21

Which nervous system controls erection?

Parasympathetic

PS - point & shoot

22

What is the most common cause of infertility?

Male infertility

for a variety of reasons

23

What is thought to be causing a decrease in male fertility (sperm counts)?

Environmental factors

e.g oestrogen

24

Male infertility can be ___ or ___.

obstructive

non-obstructive

25

What are some obstructive causes of male infertility?

Cystic fibrosis

Vasectomy

26

What are some non-obstructive causes of male infertility?

Undescended testes

Mumps infection

Genetic syndromes e.g Klinefelter's

Chemo/radiotherapy

Endocrine disease (virtually all of them)

27

What is a chromosomal disorder which causes male infertility?

Klinefelter syndrome

(47 XXY)

28

What is the most common endocrine cause of male infertility?

Hyperprolactinaemia

29

What chronic endocrine disease commonly causes erectile dysfunction?

Diabetes

30

Male bodybuilders who use which type of drug are at risk of male infertility?

Steroids