Neoplasia Flashcards

1
Q

A lesion that in an irreversible uncontrolled growth is called ____________

A

Neoplasia

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2
Q

Tumor means ?

A

Swelling

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3
Q

Cancer means?

A

Malignant

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4
Q

What are the two types of neoplasms

A

Benign

Malignant

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5
Q

What cells are present in neoplasms

A

Parenchymal

CT and blood vessesl

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6
Q

Parenchymal cells can be?

A

Epithelial

Mesenchymal

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7
Q

Are endothelial cells epithelial or mesenchymal?

A

Mesenchymal

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8
Q

Mesenchymal cells are derived from the ________

A

Mesoderm

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9
Q

Cells that are round to spindle shaped with scant cytoplasm

A

Mesenchymal

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10
Q

CT, muscle, and bone marrow are epithelial or mesenchymal cells?

A

Mesenchymal

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11
Q

Are mucosa and glands epithelial or mesenchymal

A

Epithelial

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12
Q

Epithelial cells are derived from?

A

Endoderm
Ectoderm
Mesoderm

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13
Q

Cells that are squamous/cuboidal/ columnar

A

Epithelial cells

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14
Q

The suffix for a benign epithelial cell neoplasm

A

-oma

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15
Q

The suffix for a benign mesenchymal cell neoplasm

A

-oma

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16
Q

The suffix for a malignant epithelial cell neoplasm

A

-carcinoma

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17
Q

The suffix for a malignant mesenchymal cell neoplasm

A

-sarcoma

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18
Q

The MDx for a neoplasm should include?

A

Location(organ)
Tissue origin
Growth behavior (benign/malignant )

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19
Q

Name it:

Deer with a benign growth on the dermis of the skin originating from fibrous CT

A

Derma fibroma

20
Q

Name it:

Dog with malignant growth in nasal cavity originating from fibrous CT

A

Nasal fibrosarcoma

21
Q

Name it

Dog with a benign growth in the dermis of the skin originating from vascular endothelium

A

Dermal hemangioma

22
Q

Name it

Dog with a malignant growth in the spleen originating fro the vascular endothelium

A

Splenic hemangiosarcoma

23
Q

Name it

Dog with a benign growth derived form the perianal gland

A

Perianal adenoma

24
Q

Name it

Dog with a malignant growth derived from perianal gland

A

Perianal adenocarcinoma

25
Q

Name it

Horse with a benign growth on the mandible

A

Mandibular osteoma

26
Q

Name it

Dog with malignant growth in the maxilla

A

Maxillary osteosarcoma

27
Q

Name it

Dog with a benign growth in the oral mucosa originating from squamous epithelial cells

A

Oral/labial papilloma

28
Q

Name it

Cat with malignant growth in the organ mucosa originating from squamous epithelial cells

A

Oral squamous cell carcinoma

29
Q

Name it

Cow with malignant growth in the lymph node

A

Lymphoma or lymphosarcoma

30
Q

Name it

Ovarian tumor derived from more than 1 cell lineage

A

Ovarian teratoma

31
Q

The extent to which tumor cells resemble normal parenchymal cells

A

Differentiation

32
Q

A well-differentiated tissue will resemble what?

A

The tissue of origin

33
Q

Is earlier or later arrest associated with malignancy

A

Earlier

34
Q

What are features of anaplasia that are observed in malignant neoplasms

A

Pleomorphic

Anisokaryosis (variable nucleus size)

Nuclear hyperchomasia (extra DNA)

high N:C ratio

Prominent nucleoli

Multiple nuclei

Abnormal mitotic figures

35
Q

What are the characteristics used to compare benign and malignant tumors

A

Differentiation
Growth rate
Local invasion
Metastasis

36
Q

Benign or Malignant??

Usually lack of differentiation
Structure atypical
Variable degree of anaplasia

A

M

37
Q

Benign or Malignant ??

Slow, progressive evasion
Rare mitotic figure
Normal mitotic figure

A

B

38
Q

Benign or Malignant??

Slow/rapid growth
Erratic growth rate
Numberous/abnormal mitotic figures

A

M

39
Q

Benign or Malignant??

Cohesive and expansile growth
Capsule often present

A

B

40
Q

Benign or Malignant?

Infiltrative growth
Usually no capsule

A

M

41
Q

Benign or Malignant??

Metastatic

A

M

42
Q

Benign or Malignant ??

Structure similar to tissue
Slow, progressive expansive
Cohesive and expansile growth

A

Benign

43
Q

What is the most solid criteria for determining benign/malignant?

A

Metastasis

44
Q

What is more fatal, benign or Malignant?

A

Trick question
Can be both

Eg benign in the brain => death

45
Q

Is a cell with an abnormal mitotic figure benign or Malignant?

A

M

46
Q

What is the mitotic index

A

Number of mitosis in 10 high power fields