Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

RUSVM Pathology I > #DermTerms > Flashcards

#DermTerms Flashcards

1
Q

Palpable elevation filled with clear fluid

A

Vesicle <1cm

Bulla >1cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are causes of vesicle/bulla formation

A

Auto-immune dermatoses
Viral infection
Chemical irritants
Burns

(Degeneration/necrosis or inflammation/repair)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What three changes can lead to formation of a vesicle/bulla?

A 
Intercellular edema (spongiosis)
Intracellular edema (hydropic degeneration 
Disruption of intracellular junctions (acantholysis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Spongiosis means

A

Intercellular edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Acantholysis means?

A

Disruption of tight junctions ->then we fill up with fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is a palpable elevation filled with pus?

A

Pustule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What usually causes pustules?

A

Leukocyte infiltrate (inflammation and repair)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Dried exudate, serum, blood, or scale is called ????

A

Crust

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What causes crust formation?

A

Disorders of keratiniztion
Severe pustular dermatitis
Secondary to ulcer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is a palpable, solid, elevated mass <1cm

A

Papule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What re the causes of papules?

A

Infiltrate of inflammatory cells
Infiltrate of neoplastic cells
Epidermal hyperplasia
Deposit of mineral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

A papule that is >1cm is called?

A

Nodule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is a plaque

A

Coalesced papules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Loss of epidermis with exposure of dermis is called?

A

Ulcer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Ulcers are caused by…..

A

Secondary to

  • epidermal necrosis
  • inflmmation
  • infarction
  • neoplasia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

___________ is an accumulation of losse keratinized cells

A

Scale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Cause of scale

A

Disorders of keratinizaiton

Chronic dermatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

__________ is a circular rim of scale that occurs secondary to rupture of a vesicle, pustule, or papule

A

Epidermal collarette

19
Q

Thickening and hardening of the skin, usually see criss cross pattern

A

Lichenificiation

20
Q

What are the causes of lichenification?

A

Chronic irritation/ inflammation

21
Q

When should biopsy be collected?

A

Early, before treatment

22
Q

What should you not do when collecting a skin biopsy?

A

Surgically prep the site
Grasp with forceps
Biopsy the center of a lesion
Hold out on history

23
Q 
You see the following skin lesions
Edema 
Erythema 
Alopecia 
Crusting 
Ulceration

What is the likely pathological processes?

A

Degeneration and necrosis

Inflammatory

24
Q

What is the pathogenesis of photosensitization?

A

UV light absorbed by photodynamic chemicals in skin -> free radical damage -> epidermal necrosis of lightly pigmented or sparsely haired skin

25
Q

What are the types of primary photosensitization?

A

Exogenous (type 1)
-drugs or plants containing photosensitive chemicals

Intrinsic (type 2)
-inherited deficiency of proprohyrinogen III cosynthetase -> defect in heme synthesis -> build up of prophyrins

26
Q

Secondary photosensitization is due to?

A

Type III -> hematogenous photosensitization

Poor hepatic clearance of phylloerythrin (producer of rumenal chlorophyll transformation)

Toxins causing biliary obstruction

27
Q

pale oral mucous membranes and udders that are slightly reddened are characteristics of?

A

Erythropoietin porphyria

Primary photosensitization -> deficiency of proporphyrinogen III -> deficient heme synthesis s-> porphyrins build up

28
Q

A Holstein cow presents with large patches of erythema and edema. There are also vesicles, stabbing, and ulceration. These lesions are localized mainly on the back in the light coloured hair. What is the most likely diagnosis?

A

Photosensitization

29
Q

What is the pathogenesis of acute UV light exposure

A

Sunburn

Radiation -> endothelial damage and cytokine production -> erythema -> vesicles -> soughing of necrotic skin

30
Q

Chronic UV light exposure can lead to __________

A

Solar/actinic keratosis

31
Q

T/F: animals with actinic keratosis are more at risk for neoplasia due to direct DNA injury and subsequent mutations

A

T

32
Q

Nonpigmented and sparsely haired skin is erythemaous, has comedones, crust, is thickened.

What am i??

A

Solar/ actinic keratosis

33
Q

What is a comedone?

A

Black head

Pore that is distended and filled with keratin

34
Q

The rupture of a comedone is called?

A

Furunculosis

35
Q

Thermal burn that is on the epidermis, reddened/darkened necrotic epidermis, will completely heal

A

1st degree

36
Q

Thermal burn that involves the epidermis and dermis and has vesicle formation. Some adnexa are preserved allowing regeneration and some scaring

A

2nd degree

37
Q

Thermal burn that involves epidermis, dermis, and subcutis. Necrotic tissue sloughs off, followed by granulation tissue and leaves a scar

A

3rd degree

38
Q

_________ burns are caused by body or wound secretions, application of drugs, exposure to acids, soaps, detergents, or irritant plants

A

Chemical

39
Q

T/F: chemical burns are usually mild irritants and must penetrate hair and protective epidermal layers to have effect

A

True

40
Q

Erythema multiforme and toxic epidermal necrolysis is due to what

A

Type IV hypersensitivity towards antigens of the surface keratinocytes inducing apoptosis

41
Q

What is the difference between erythema multifome and toxic epidermal necrolysis

A

EM

  • mild
  • single cell apoptosis +/- lymphocyte satellitosis

TEN

  • severe
  • sheets of apoptotic/necrotic cells resembling a burn
42
Q

Wide spread coalescing erythematous macules -> vesicles and ulcers

A

Erythema multifome and toxic epidermal necrolysis

43
Q

When you see a burn, your pathological process is _______________

A

Degeneration/necrosis

RUSVM Pathology I (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions