2.3.1 Bone and Tumor Pathology II Flashcards

1
Q

What is this an image of?

A

Osteosarcoma

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2
Q

What is this an image of?

A

Enchondroma

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3
Q

What is this an image of?

A

Ewing’s Sarcoma

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4
Q

What are some of the genetic mutations that are associated with Ewing’s Sarcoma?

A

HAVE TO KNOW!

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5
Q

What is this an image of?

A

Osteosarcoma

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6
Q

What is this an image of?

A

Chondrosarcoma

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7
Q

What are some other characteristics of Ewing’s Sarcoma?

A
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8
Q

What is your diagnosis?

A

Ewing’s Sarcoma

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9
Q

Why could you see hypercalcemia in metastatic cancers to the bone?

A
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10
Q

What is this an image of?

A

Chondrosarcoma

Bluish white color

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11
Q

What are some of the characteristics of Metastatic Carcinomas?

A
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12
Q

What are some of the characteristics of a chondrosarcoma?

A

40 year old or older

Central skeleton - pelvis, shoulder or ribs

Malignant hyaline or myxoid

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13
Q

What is this an image of?

A

Chondrosarcoma

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14
Q

What are these two images?

A

Left side metastatic renal cell carcinoma

Right - normal bone marrow

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15
Q

What is this an image of?

A

Normal cartilage

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16
Q

What is an image of?

A

Multiple myeloma is the red

17
Q

What is this an image of?

A

Chondrosarcoma

18
Q

What is this an image of and what it is indicative of?

A

RBCs have stacked together in long chains. This is known as Rouleaux’s sign. It occurs when there are increased serum proteins. Particularily fibrinogen and globulins. These long chains of RBCs tend to sediment more easily.

19
Q

Fill these in.

A

Breast - mixed lytic and blastic

Lung - Lytic

Thyroid - lytic

Kidney - lytic

Prostate - blastic

20
Q

What mutations are common in osteosarcoma?

A

p53 and RB

21
Q

What is this an image of?

A

Osteosarcoma

22
Q

What are the most common locations for osteosarcoma to appear?

A
23
Q

What is the important area of this image? What is it?

A

Upper right area

Metastatic Renal Cell Carcinoma

Bottom is normal bone marrow

24
Q

What are characteristics X ray findings of a chondrosarcoma?

A

Punctate calcifications and soft tissue mass

25
Q

What are the characteristics of Multiple Myeloma?

A
26
Q

What is the most common location on the bone for an osteosarcoma to appear?

A

Metaphysis

27
Q

What is your diagnosis?

A

Multiple Myeloma - WHO KNEW!

28
Q

What is this an image of?

A

Ewing’s Sarcoma

29
Q

What is this an image of?

A

Chondrosarcoma

30
Q

What is this an image of?

A

Osteosarcoma

31
Q

What is this an image of?

A

Osteosarcoma

32
Q

What is this an image of?

A

Osteoids

33
Q

What is this an image of?

A

Ewing’s Sarcoma

34
Q

What are the characteristics of Ewing’s Sarcoma?

A