Acromegaly Flashcards

1
Q

Acromegaly is a disease leading to excessive secretion of what hormone

A

Growth hormone

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2
Q

What secretes Gh

A

Anterior pituitary gland

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3
Q

What regulates GH production

A

GH- releasing hormone and somatostatin- both released from the hypothalamus

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4
Q

What is the most common cause of increased GH secretion

A

Pituitary tumour

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5
Q

What are the symptoms of acromegaly

A
Sweating
Headaches
Oligo/amenorrhoea
Infertility
Proximal muscle weakness
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6
Q

What are the signs of acromegaly

A
Coarsening of facial features with prominent lower jaw and supra orbital ridges
Increased interdendal spacing
Enlarged tongue
Doughy, spade like hands
Carpel tunnel
Hoarse voice
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