hybridomas and Monoclonal antibodies

Question 1

polyclonal antibodies

Answer 1

complex mixtures by a single animal host, not reproducible from one host to another, different affinity and epitope specificity

Question 2

T/F: Polyclonal antibodies are more likley to exhibit cross reactivity with interfering substances

Answer 2

True

Question 3

What is taken from the mouse to help create hybridomas

Answer 3

splenocytes

Question 4

What gene allows for HAT medium to select for cells that will be used

Answer 4

HGPRT+

Question 5

T/F: Monoclonal antibodies are are only one type

Answer 5

True

Question 6

T/F: It is easy to make monoclonal antibodeis against antigents that the host is tolerant to

Answer 6

False: it is quite difficult and almost impossible

Question 7

How many epitopes can a monoclonal antibody recognize

Answer 7

1

Question 8

biosimilar

Answer 8

biopharmaceutical product that is almost an identical copy of an original product that is manufactured by a different company