Chapter 18: Table 18.11 (PBC Vs PSC)

Question 1

What is the gender predominance for Primary sclerosing cholangitis

Answer 1

Male (70%)

Question 2

What is the radiological finding in Primary Biliary Cirrhosis

Answer 2

Normal

Question 3

What is the median age for Primary sclerosing cholangitis

Answer 3

30

Question 4

What are the associated conditions with Primary sclerosing cholangitis

Answer 4

• IBD (70%)

- Pancreatitis (25%)

Question 5

What are the serological for Primary Biliary Cirrhosis

Answer 5

AMA-positive (95%)
ANA-positive (50%)
ANCA-postive (40%)

Question 6

What is the serology for Primary sclerosing cholangitis

Answer 6

ANCA-positive (65%)
ANA-Positive (6%)
AMA-positive (5%) low titer

Question 7

What are the radiological findings in Primary sclerosing cholangitis

Answer 7

-Stricutres and beading of the large bile ducts, pruning of the smaller bile ducts

Question 8

What is the duct lesion for Primary Biliary Cirrhosis

Answer 8

Florid duct lesions with loss of only the small ducts

Question 9

What is the clinical course for primary biliary cirrhosis

Answer 9

Progressive

Question 10

What are the duct lesions in Primary sclerosing cholangitis

Answer 10

Inflammatory destruction of extrahepatic and large intrahepatic ducts, with fibrotic damage to medium and small ducts

Question 11

What is the gender preference for Primary Biliary Cirrhosis

Answer 11

Female (90%)

Question 12

What is the clinical course for Primary sclerosing cholangitis

Answer 12

Unpredictable but progressing

Question 13

What is the median age for Primary Biliary Cirrhosis

Answer 13

50

Question 14

What are the associated conditions with Primary Biliary Cirrhosis

Answer 14

Sjogren (70%)
Thyroid disease (20%)
Scleroderma (5%)