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Robbins Pathology GI (Chptr 16,17,18,19) > Chapter 17- Table 17.11 > Flashcards

Chapter 17- Table 17.11 Flashcards

1
Q

With regards to Familial adenomatous polyposis: what is the predominant side

A

None

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2
Q

With regards to sporadic colon cancer: what is the histology

A

Tubular, villous, typical adenocarcinoma

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3
Q

With regards to MYH-associated polyposis: what is the molecular defect

A

DNA mismatch repair

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4
Q

With regards to hereditary nonpolyposis colorectal cancer: what is the transmission

A

Autosomal dominant

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5
Q

With regards to sporadic colon cancer: what is the transmission

A

Non

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6
Q

With regards to hereditary nonpolyposis colorectal cancer: what is the histology

A

Sessile serrated adenoma

Mucinous adenocarcinoma

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7
Q

With regards to Familial adenomatous polyposis: what is the target gene

A

APC

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8
Q

With regards to Familial adenomatous polyposis: what is the histology

A

Tubular, villous, typical adenocarcinoma

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9
Q

With regards to Familial adenomatous polyposis: what is the molecular defect

A

APC/Wnt pathway

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10
Q

With regards to sporadic colon cancer: what is the target gene

A

APC

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11
Q

With regards to sporadic colon cancer: what is the molecular defect

A

APC/Wnt

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12
Q

With regards to hereditary nonpolyposis colorectal cancer: what is the molecular defect

A

DNA mismatch repair

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13
Q

With regards to MYH-associated polyposis: what is the histology

A
  • Sessile serrated adenoma

- mucinous adenocarcinoma

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14
Q

With regards to Familial adenomatous polyposis: what is the transmission

A

Autosomal dominant

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15
Q

With regards to hereditary nonpolyposis colorectal cancer: what is the target gene

A

MSH2, MLH1

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16
Q

With regards to hereditary nonpolyposis colorectal cancer: what is the target side

A

Right side

17
Q

With regards to MYH-associated polyposis: what is the predominant site

A

None

18
Q

With regards to sporadic colon cancer: what is the predominant site

A

Left side

19
Q

With regards to MYH-associated polyposis: what is the target gene

A

MYH

20
Q

With regards to MYH-associated polyposis: what is the transmission

A

Autosomal recessive

Robbins Pathology GI (Chptr 16,17,18,19) (32 decks)

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