Bacteriophages Flashcards

1
Q

Bacteriophages are?

A

the best-studied bacteriophages infect E.coli (gram-negative)

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2
Q

what kind of genome do the bacteriophages posses?

A

linear dsDNA genomes

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3
Q

do they have envelopes or not?

A

most are naked, but some posses lipid envelopes

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4
Q

Two types of bacteriophages?

A
  • Virulent phage

- Temperate phages

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5
Q

The virulant phages ?

A

infection of host cells walways leads to replication resulsting in host cell lysis (lytic pathway T4)

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6
Q

The temperate phages has two options ?

A

1) lytic pathway

2) lysogenic pathway (genome becomes incorporated into the bacterial host genome) (lamda does this)

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7
Q

who discovered lamda?

A

Ester lederberg

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8
Q

How is adsorption in the T4 bacteriophage?

A

T4 attaches to the core region of LPS by the tail fibers

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9
Q

Following attachment?

A

the tail sheat contracts, forcing the central core through the outer membrane

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10
Q

c quoi qui fait qu’il peut forcer son entrée ds le outer membrane?

A

tail lysozymes digest the peptidoglycan layer,forming a small pore

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11
Q

apres que the tail soit rentrer ?

A

the phage DNA is then injected into the cytoplasm of the host cell

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