Pituitary 2 Flashcards
excess cortisol is seen in what condition?
cushings
excess mineralocorticoid is seen in what condition?
cushings
excess androgen is seen in what condition?
cushings
what type of myopathy is seen in cushings?
proximal
cushings symptoms?
protein loss = proximal myopathy
osteoporosis thin skin bruising central obesity hypertension oedema
many many many more
LEMON ON MATCHSTICKS
name the test performed to SCREEN for cushings
overnight 1mg dexamethasone suppression test
urine free cortisol - 24hr urine collection
diurnal cortisol variation (midnight and 8am)
name the DEFINITIVE test to diagnose cushings
2 day 2mg/day dexamethasone suppression test
if cortisol is low then normal
if high = cushings
if the problem in cushings is in the pituitary then its cushings _______
if the problem in cushings is in the pituitary then its cushings DISEASE
name the test performed to determine what type of cushings it is
high dose dexamethasone suppression test
name the 3 types of cushings
pituitary
adrenal
ectopic
what type of cushings:
ACTH is <1
adrenal
what type of cushings:
ACTH is low
pituitary
what type of cushings:
ACTH is high
ectopic
what type of cushings:
high dose dexamethasone suppression test suppresses by 50%
pituitary
cushings treatment:
(a) pituitary
(b) adrenal
(c) ectopic
(a) pituitary - surgery/radio
(b) adrenal - adrenalectomy
(c) ectopic - remove source or bilateral adrenalectomy
