Chapter 15 Regulation Of Gene Expression Flashcards

1
Q

Prokaryotes and Eukaryotes alter gene expression in response

A

To their changing environment

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2
Q

A cell can regulate the production of enzymes by

A

Feedback inhibition or gene regulation

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3
Q

Gene expression in bacteria is controlled by a process called

A

The Operon model

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4
Q

A group of functionally related genes can be coordinately controlled by a single

A

On-off switch

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5
Q

The regulatory switch is a segment of dna called

A

An operator

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6
Q

An ________is the entire stretch of DNA that includes the operator, the promotor, and the genes they control

A

Operon

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7
Q

The Operon can be switched off by a protein

A

Repressor

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8
Q

The repressor is the product of a separate

A

Regulatory gene

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9
Q

A _________ is a molecule that cooperates with a repressor protein to switch an Operon off

A

Corepressor

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10
Q

Two types of negative gene regulation

A

Repressible

Inducable

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11
Q

A repressible Operon is usually

A

On

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12
Q

An inducible Operon is usually

A

Off

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13
Q

A molecule called the__________ inactivates the repressor

A

Inducer

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14
Q

Inducible enzymes usually function in

A

Catabolic pathways

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15
Q

Repressible enzymes usually function in

A

Anabolic pathways

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16
Q

Differential gene expression

A

The expression of different genes by cells within the same genome

17
Q

Gene expression is commonly controlled at

A

Transcription

18
Q

Histone Acetylation

A

Acetyl groups are attached to positively charged lysine and histone tails

19
Q

DNA methylation

A

Is the addition of methyl groups to certain bases in DNA, usually cytosine

20
Q

Epigenetic Inheritance

A

The inheritance of traits transmitted by mechanisms not directly involving the nucleotide sequence

21
Q

Control Elements

A

Segments of non coding DNA that serve as binding sites for transcription factors

22
Q

Enhancers

A

Distal control elements may be far from a gene or located in an intron

23
Q

Alternative RNA splicing

A

Different mRNA molecules are produced from the same primary transcript

24
Q

Eukaryotic mRNA generally survives longer than

A

Prokaryotic mRNA

25
Q

MicroRNA

A

Small, single stranded RNA molecules that can bind to complementary mRNA sequences

26
Q

The phenomenon of inhibition of gene expression by small interfering RNA is called

A

RNA interference

27
Q

Nucleic Acid Hybridization

A

The base pairing of a strand of nucleic Acid to its complementary sequence

28
Q

Nucleic Acid Probe

A

Short single stranded DNA or RNA

29
Q

In Situ Hybridization

A

Seeing in place in the intact organisms

30
Q

Reverse transcriptase polymerase

A

Method for comparing the amounts of specific mRNA in several different samples

It turns sets of mRNA into double stranded DNA with the corresponding sequences

31
Q

Complementary DNA

A

A DNA copy of mRNA

32
Q

DNA Microassays

A

Contains tiny amounts of many single stranded DNA fragments affixed to the slide in a grid