Basics Flashcards
1
Q
Whats does GnRH stimulate?
A
LH and FSH from ant pituitary
2
Q
What does FSH do?
A
stimulate follicular recruitment and development
3
Q
What does LH do?
A
maintains the dominant follicle, induces its maturation and ovulation and stimulates CL function
4
Q
What does Oestradiol from granulosa cells do?
A
2nd sexual characteristics and reproductive organs
Negative feedback control of LH and GnRH (except late follicular phase = LH surge)
Stimulates endometrium
Negative control of FSH
5
Q
What does progesterone from Corpus luteum do?
A
Maintains endometrium
Negative feedback of HPO
6
Q
What are the targets for oestrogen?
A
CNS Anterior pituitary/hypothalamus Fat distribution Mammary glands Bone maturation Gonads Systemic (protein met, carbs, lipids, water and electrolytes, blood clotting)
7
Q
What are the targets for testosterone?
A
Skin Liver = serum proteins Sexual organs Brain Muscles Kidney = erythroptorein production Bone marrow Bone
