In the regulation of vascular smooth muscle tone, calcium enters the cell through which channel?
L-type Ca2+ channel
What does Ca2+ bind to in the process of activating MLCK?
Which enzyme does the calcium-calmodulin complex activate?
MLCK (myosin light chain kinase)
What does MLCK do, and what effect does this produce?
Phosphorylates myosin light chains, producing contraction
In the process of relaxation in vascular smooth muscle, what enzyme activates myosin-light-chain-phosphatase?
Protein kinase G
What activates Protein kinase G, which activates an enzyme during vascular smooth muscle relaxation?
What does activated Myosin-light-chain-phosphatase do, and what effect does this produce?
Dephosphorylates myosin light chains producing relaxation.