Oxytocin

Question 1

Oxytocin

Class

Answer 1

• Hormone

Question 2

Oxytocin

MOA

Answer 2

• Increases uterine contractions

Question 3

Oxytocin

Indications

Answer 3

• Postpartum hemorrhage after infant and placental delivery

Question 4

Oxytocin

Contraindications

Answer 4

• Presence of second fetus
• Unfavorable fetal position
• Hypersensitivity

Question 5

Oxytocin

Adverse reactions

Answer 5

• Hypotension
• Hypertension
• Tachycardia
• Arrythmias
• Angina pectoris
• SZ
• N/V
• Uterine rupture
• Anaphylaxis
• Anxiety

Question 6

Oxytocin

Drug interactions

Answer 6

• Other vasopressors may potentiate hypertension

Question 7

Oxytocin

Dosage

Answer 7

• IM administration:
  
  • 3-10 units after delivery of placenta
• IV administration:
  
  • Mix 10-40 units in 1000 mL if nonhydrating diluent: Infused at 20-40 milliunits/min
  • Titrate to severity of bleeding and uterine response

Question 8

Oxytocin

Duration of action

Answer 8

• Onset:
  
  • IM 3-5 min
  • IV immediate
• Peak: varies
• Duration:
  
  • IM 30-60 min
  • IV 20 min after infusion discontinued

Question 9

Oxytocin

Special Considerations

Answer 9

• Preg Cat: X
• Monitor vital signs, including fetal heart rate and uterine tone