Ipratroprium Bromide (Atrovent) COPY Flashcards
1
Q
Ipratroprium Bromide (Atrovent)
Class
A
- Anticholinergic
2
Q
Ipratroprium Bromide (Atrovent)
Mechanism of action
A
- Antagonizes action of ACh on bronchial smooth muscles resulting in bronchodilation
3
Q
Ipratroprium Bromide (Atrovent)
Indications
A
- Maintenance treatment of bronchospasm in COPD/asthma pt
- Can be used alone or in combination with other bronchodilators
4
Q
Ipratroprium Bromide (Atrovent)
Contraindications
A
- Allergic to Atrovent, atropine, anticholinergic derivatives, soy & peanuts
- Do not give to pt younger than 12 yo
5
Q
Ipratroprium Bromide (Atrovent)
Adverse reactions
A
- H/A
- Papitations
- Nervousness
- Dizziness
- Aggravates HTN
- Epistaxis
- Exacerbates cough symptoms
- Blurred vision, conjunctivitis, local irritation
- Nasal dryness, congestion and burning
- Taste perversion, hoarsness, pharyngitis
6
Q
Ipratroprium Bromide (Atrovent)
Drug interactions
A
- None in emergency setting
- Safe when used in conjunction with beta adrenergic bronchodilators
- Can be used with pulmonary medications like methylxanthines and corticosteroids
7
Q
Ipratroprium Bromide (Atrovent)
Dosage and administration
A
- PT must be at least 12 yo
- 500µg 3-4 times a day by NEB, with doses 6-8 hrs apart
- Can be mixed in the NEB with albuterol or metaproternol if used within 1 hr
8
Q
Ipratroprium Bromide (Atrovent)
Duration of action
A
- Onset: 15-30 min
- Peak effect: 1-2 hrs
- Duration of action: 4-5 hrs
9
Q
Ipratroprium Bromide (Atrovent)
Special considerations
A
- Pregnancy: Cat B
- Safety in children younger than 12 yo has not been established
