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BB LEC > ABOSystem > Flashcards

ABOSystem Flashcards

1
Q

Two major Blood Groups

A

ABO and Rh

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2
Q

Arrange from Most common to rare: A, B, O, AB

A

O, A, B, AB

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3
Q

Anti-A Dye

A

Bromocresol Blue

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4
Q

Anti B dye

A

Acriflavine Dye

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5
Q

Principle of blood grouping

A

Direct agglutination

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6
Q

Shelf life of A1 and B cells

A

7 days

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7
Q

Method used to break the interaction between the antigen and antibody

A

Elution

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8
Q

Interaction between soluble antigens and antibody to form insoluble complexes

A

Precipitation

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9
Q

Naturally occurring antibody

A

IgM

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10
Q

Abo stimulated in what Immunoglobulins?

A

IgG

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11
Q

True or False

ABO antibodies produce strong direct agglutination reaction during ABO testing.

A

True

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12
Q

attraction that a SPECIFIC antibody possessed to its corresponding antigen

A

Affinity

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13
Q

attraction/reaction between
MULTIPLE or MANY antigen and antibody reactions;

A

Avidity

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14
Q

True of False

The strength of reaction if greater in AVIDITY THAN AFFINITY

A

True

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15
Q

Antibody in blood types A and B is

A

IgM

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16
Q

Antibody in blood type O

A

IgG

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17
Q

It is the detectable expression of a certain gene on the genotype

A

Phenotype

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18
Q

unique sequence of DNA on the cell of a person

A

Genotype

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19
Q

Phenotype: A2 Genotype:?

A

A2O A2A2

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20
Q

Phenotype: A1B Genotype?

A

A1B

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21
Q

Phenotype: A1O Genotype?

A

A1

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22
Q

H & Se genes located at what chromosomes

A

Chromosomes 19

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23
Q

Reactivity of Anti H Anti Sera or Anti H lectin with ABO blood groups

A

O>A2>B>A2B>A1>A1B

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24
Q

Substance that is capable of stimulating an immune response, specifically activating lymphocytes

A

Antigen

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25
Q

Location of Antigen:
Binding site:
Solubility:

A

-Surface of RBCs
-Epitope
-insoluble

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26
Q

Location of Antibodies:
Binding site:
Solubility:

A

-In Plasma
-Paratope
-Soluble

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27
Q

Part of antigen attaches to antibody? and its other term

A

Epitope: AKA Antigenic Determinant

28
Q

Part of antibody that recognises and binds to antigen

A

Paratope

29
Q

This is exist when the result of red blood cells test (antigen) do not agree with the serum test (antibodies)

A

ABO Discrepancies

30
Q

What group is associated with unexpected reactions in the reverse grouping due to weakly reacting or missing antibodies.

A

Group 1

31
Q

What group/discrepancies are more common

A

Group 1

32
Q

associated with unexpected reactions in the forward grouping due to weakly reacting or missing antigens.

A

Group 2

33
Q

This group of discrepancies is probably the LEAST frequently encountered.

A

Group 2

34
Q

These discrepancies between forward and reverse groupings are caused by protein or plasma abnormalities.

A

Group 3

35
Q

What group in ABO Discrepancies result in rouleaux formation and pseudoagglutination?

A

Group 3

36
Q

These discrepancies between forward and reverse groupings are due to miscellaneous problems.

A

Group 4

37
Q

This is an example of what group in ABO Discrepancies?

Cold reactive autoantibodies

A

Group 4

38
Q

This is an example of what group in ABO Discrepancies?

Patient has circulating RBCs of more than one ABO group due to RBC transfusion or marrow/stem cell transplant.

A

Group 4

39
Q

This is an example of what group in ABO Discrepancies?

Unexpected ABO isoagglutinins
Unexpected non-ABO alloantibodies

A

Group 4

40
Q

This is an example of what group in ABO Discrepancies?

Multiple myeloma “stacked coins appearance”

A

Group 3

41
Q

This is an example of what group in ABO Discrepancies?

Waldenstrom’s Macroglobulinemia

A

Group 3

42
Q

This is an example of what group in ABO Discrepancies?

Advance cases of Hodgkin Lymphoma

A

Group 3

43
Q

This is an example of what group in ABO Discrepancies?

Acquired B phenomenon

A

Group 2

44
Q

This is an example of what group in ABO Discrepancies?

Excess amount of blood group-specific soluble substances (BGSS)

A

Group 2

45
Q

This is an example of what group in ABO Discrepancies?

Leukemia due to weakened A or B antigens

A

Group 2

46
Q

This is an example of what group in ABO Discrepancies?

Newborns
Elderly patients
Leukemia or Lymphoma
Hypogammaglobulinemia

A

Group 1

47
Q

This is an example of what group in ABO Discrepancies?

CHIMERISM

A

Group 1

48
Q

A rare group, presence of two cell population in single individual like fraternal twins

A

CHIMERISM

49
Q

Distribution and Function of IgA

A

Intravascular and Secretion
Protect mucus membranes

50
Q

Distribution and Function of IgD

A

Lymphocytes surfaces, Unknown

51
Q

Distribution and Function of IgE

A

Basophils Mast Cells Nasal Secretions
Protect against parasites

52
Q

Distribution and Function of IgG

A

Intravascular and Extravascular
Secondary Response

53
Q

Distribution and Function of IgM

A

Intravascular
Primary Response

54
Q

Percent total of IgA in immunoglobulins

A

15%

55
Q

Percent total of IgD in immunoglobulins

A

0.2%

56
Q

Percent total of IgE in immunoglobulins

A

0.002%

57
Q

Percent total of IgG in immunoglobulins

A

75%

58
Q

Percent total of IgM in immunoglobulins

A

10%

59
Q

Anti-A1 Lectin (A subgroups) derived from?

A

Dolichus Biflorus

60
Q

Anti-B Lectin (B subgroups) derived from?

A

Banderaea Siimplicifolia

(Rarely performed because it is very rare)

61
Q

Anti H Lectin (H subgroups) derived from?

A

Ulex Europaeus

62
Q

Phenotype that lacks normal expression of the ABH antigens because of inheritance of the hh genotype.

A

Bombay

63
Q

It represents the inheritance of a double dose of the h gene, producing the very
rare genotype hh.

A

Bombay

64
Q

T/F
Bombay was first reported by Bhende in 1952.

A

True

65
Q

T/F

The Bombay Phenotype is inherited as an autosomal recessive trait.

A

True

66
Q

Rare phenotypes in which the RBCs are completely devoid of H antigens or have small amounts of H antigen present.

A

Parabombay

BB LEC (8 decks)

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