ABOSystem

Question 1

Two major Blood Groups

Answer 1

ABO and Rh

Question 2

Arrange from Most common to rare: A, B, O, AB

Answer 2

O, A, B, AB

Question 3

Anti-A Dye

Answer 3

Bromocresol Blue

Question 4

Anti B dye

Answer 4

Acriflavine Dye

Question 5

Principle of blood grouping

Answer 5

Direct agglutination

Question 6

Shelf life of A1 and B cells

Answer 6

7 days

Question 7

Method used to break the interaction between the antigen and antibody

Answer 7

Elution

Question 8

Interaction between soluble antigens and antibody to form insoluble complexes

Answer 8

Precipitation

Question 9

Naturally occurring antibody

Answer 9

IgM

Question 10

Abo stimulated in what Immunoglobulins?

Answer 10

IgG

Question 11

True or False

ABO antibodies produce strong direct agglutination reaction during ABO testing.

Answer 11

True

Question 12

attraction that a SPECIFIC antibody possessed to its corresponding antigen

Answer 12

Affinity

Question 13

attraction/reaction between
MULTIPLE or MANY antigen and antibody reactions;

Answer 13

Avidity

Question 14

True of False

The strength of reaction if greater in AVIDITY THAN AFFINITY

Answer 14

True

Question 15

Antibody in blood types A and B is

Answer 15

IgM

Question 16

Antibody in blood type O

Answer 16

IgG

Question 17

It is the detectable expression of a certain gene on the genotype

Answer 17

Phenotype

Question 18

unique sequence of DNA on the cell of a person

Answer 18

Genotype

Question 19

Phenotype: A2 Genotype:?

Answer 19

A2O A2A2

Question 20

Phenotype: A1B Genotype?

Answer 20

A1B

Question 21

Phenotype: A1O Genotype?

Answer 21

A1

Question 22

H & Se genes located at what chromosomes

Answer 22

Chromosomes 19

Question 23

Reactivity of Anti H Anti Sera or Anti H lectin with ABO blood groups

Answer 23

O>A2>B>A2B>A1>A1B

Question 24

Substance that is capable of stimulating an immune response, specifically activating lymphocytes

Answer 24

Antigen

Question 25

Location of Antigen: Binding site: Solubility:

Answer 25

-Surface of RBCs -Epitope -insoluble

Question 26

Location of Antibodies: Binding site: Solubility:

Answer 26

-In Plasma -Paratope -Soluble

Question 27

Part of antigen attaches to antibody? and its other term

Answer 27

Epitope: AKA Antigenic Determinant

Question 28

Part of antibody that recognises and binds to antigen

Answer 28

Paratope

Question 29

This is exist when the result of red blood cells test (antigen) do not agree with the serum test (antibodies)

Answer 29

ABO Discrepancies

Question 30

What group is associated with unexpected reactions in the reverse grouping due to weakly reacting or missing antibodies.

Answer 30

Group 1

Question 31

What group/discrepancies are more common

Answer 31

Group 1

Question 32

associated with unexpected reactions in the forward grouping due to weakly reacting or missing antigens.

Answer 32

Group 2

Question 33

This group of discrepancies is probably the LEAST frequently encountered.

Answer 33

Group 2

Question 34

These discrepancies between forward and reverse groupings are caused by protein or plasma abnormalities.

Answer 34

Group 3

Question 35

What group in ABO Discrepancies result in rouleaux formation and pseudoagglutination?

Answer 35

Group 3

Question 36

These discrepancies between forward and reverse groupings are due to miscellaneous problems.

Answer 36

Group 4

Question 37

This is an example of what group in ABO Discrepancies? Cold reactive autoantibodies

Answer 37

Group 4

Question 38

This is an example of what group in ABO Discrepancies? Patient has circulating RBCs of more than one ABO group due to RBC transfusion or marrow/stem cell transplant.

Answer 38

Group 4

Question 39

This is an example of what group in ABO Discrepancies? Unexpected ABO isoagglutinins Unexpected non-ABO alloantibodies

Answer 39

Group 4

Question 40

This is an example of what group in ABO Discrepancies? Multiple myeloma “stacked coins appearance”

Answer 40

Group 3

Question 41

This is an example of what group in ABO Discrepancies? Waldenstrom’s Macroglobulinemia

Answer 41

Group 3

Question 42

This is an example of what group in ABO Discrepancies? Advance cases of Hodgkin Lymphoma

Answer 42

Group 3

Question 43

This is an example of what group in ABO Discrepancies? Acquired B phenomenon

Answer 43

Group 2

Question 44

This is an example of what group in ABO Discrepancies? Excess amount of blood group-specific soluble substances (BGSS)

Answer 44

Group 2

Question 45

This is an example of what group in ABO Discrepancies? Leukemia due to weakened A or B antigens

Answer 45

Group 2

Question 46

This is an example of what group in ABO Discrepancies? Newborns Elderly patients Leukemia or Lymphoma Hypogammaglobulinemia

Answer 46

Group 1

Question 47

This is an example of what group in ABO Discrepancies? CHIMERISM

Answer 47

Group 1

Question 48

A rare group, presence of two cell population in single individual like fraternal twins

Answer 48

CHIMERISM

Question 49

Distribution and Function of IgA

Answer 49

Intravascular and Secretion Protect mucus membranes

Question 50

Distribution and Function of IgD

Answer 50

Lymphocytes surfaces, Unknown

Question 51

Distribution and Function of IgE

Answer 51

Basophils Mast Cells Nasal Secretions Protect against parasites

Question 52

Distribution and Function of IgG

Answer 52

Intravascular and Extravascular Secondary Response

Question 53

Distribution and Function of IgM

Answer 53

Intravascular Primary Response

Question 54

Percent total of IgA in immunoglobulins

Answer 54

15%

Question 55

Percent total of IgD in immunoglobulins

Answer 55

0.2%

Question 56

Percent total of IgE in immunoglobulins

Answer 56

0.002%

Question 57

Percent total of IgG in immunoglobulins

Answer 57

75%

Question 58

Percent total of IgM in immunoglobulins

Answer 58

10%

Question 59

Anti-A1 Lectin (A subgroups) derived from?

Answer 59

Dolichus Biflorus

Question 60

Anti-B Lectin (B subgroups) derived from?

Answer 60

Banderaea Siimplicifolia (Rarely performed because it is very rare)

Question 61

Anti H Lectin (H subgroups) derived from?

Answer 61

Ulex Europaeus

Question 62

Phenotype that lacks normal expression of the ABH antigens because of inheritance of the hh genotype.

Answer 62

Bombay

Question 63

It represents the inheritance of a double dose of the h gene, producing the very rare genotype hh.

Answer 63

Bombay

Question 64

T/F Bombay was first reported by Bhende in 1952.

Answer 64

True

Question 65

T/F The Bombay Phenotype is inherited as an autosomal recessive trait.

Answer 65

True

Question 66

Rare phenotypes in which the RBCs are completely devoid of H antigens or have small amounts of H antigen present.

Answer 66

Parabombay