Acidosis and Alkalosis Flashcards Preview

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Flashcards in Acidosis and Alkalosis Deck (37)
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1

Fat tissue holds ______ water so obese people hold _______

less
Lower water content by weight

2

Fluid compartments for average 70 kg man

25 L ICF
15 L ECF (10 interstital and 5 blood)

3

As water passed from blood to urine _____

Water replenished from ICF

4

ICF higher electrolytes

Potassium, inorganic phisphate

5

ECF Higher electrolyters

Na, Cl, HCO3

6

mEq equation

mmol X Abs(charge)

7

Buffers consist of

Weak acid and conjugate base

8

Buffers can compensate

WIthin 1 pH unit of pKa of acid

9

3 sources of acids in adults

Non-volatile (digestive)
Organic (normal metabolism)
CO2 (from O2 use by muscles)

10

CO2 combines with _____ to form _____

H2O
H2CO3

11

Non-volatile acids quantity

Minor (50-100 mEq)

12

Organic acids concentration

Thousands of mmol per day
Metabolized to neutral organic compounds

13

Organic acid concentration of ECF

Low and at steady state

14

Carbon dioxide is ____

major buffering system of ECF

15

Acid base balance from rapid to long-term

Normal pulmonary excretion of CO2
Metabolic utilization of organic acids
Renal excretion of non-volatile acids

16

Acidemia vs. acidosis (same with alkalosis and alkalemia()

Acidemia - blood pH below normal range
Acidosis - process that lowers ECF pH

17

Metabolic acidosis/alka

Changes serum HCO3 concentrations and pH

18

Metabolic acid/alk response

Respiratory response moving pCO2 in same direction as HCO3 change

19

Respiratory acid/alk

CHanges arterial CO2 and pH

20

Respiratory response

Initial - Change in HCO3 by buffering
Later - Renal response changing HCO3 in same direction of pCO2

21

Met acid - cause and response

cause - HCO3 dec
Resp - pCO2 dec via resp

22

Resp acidosis cause and resp

cause - pCO2 inc
Acute - HCO3 inc via buffer
Chronic - HCO3 inc via renal

23

Met alkalosis - cause and response

Cause - HCO3 inc
Resp - pCO2 in via resp

24

Resp alkalosis - cause and response

Cause - pCO2 dec
Acute - HCO3 dec via buffer
Chronic - HCO3 dec via renal

25

hyperventaltion incdicates

metabolic acidosis

26

Deeper, slower breaths indicates

Metabolic alkalosis

27

Initial diagnosis

Serum electorlyters (HCO3)

28

Definitive diagnosis

Serum pH and pCO2

29

Essential to collect

Patient hisotry

30

Vomiting causes

Metabolic alkalosis