Acne Vulgaris Flashcards

1
Q

Acne vulgaris

A

Follicular plugging

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2
Q

Pathogenesis

A

Increased androgens in men
Increased androgenic properties of progesterone in women
Follicular keratinization: hyperkeratotic plugs in follicular opening
Hyperplasia of sebaceous glands
Propionibacterium acne in follicles

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3
Q

Propionibacterium acnes releases what

A

Lipase
It splits free fatty acids and releases inflammatory mediators

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4
Q

Acne vulgaris classification

A

Acne comedonica
Acne papulopustulosa

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5
Q

Acne comedonica

A

Open comedon - white heads
Closed comedon - blackheads

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6
Q

Comedones

A

Comedones develope in sebaceous follicles on face, chest and mid back
With small hair and large sebaceous glands

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7
Q

Black colour in comedones are from

A

Follicle melanin ,not dirt

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8
Q

Most common sites for comedones are

A

Forehead
Cheeks
Perioral region

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9
Q

Acne papulopustulosa

A

Comedone ruptures
Neutrophils are attracted
And pus

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10
Q

Therapy

A

Retinoids
Isotretinoin
Benzoyl peroxide
Tetracycline
Anti androgens

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