Ichthyosis Vulgaris Flashcards
1
Q
Ichthyosis vulgaris
A
Formation of keratohyalin granules
Delayed destruction of desmosomes
Because of absence of profilaggrin and filaggrin
Leads to retention hyperkeratosis
2
Q
Clinical features
A
Starts in 1st year of life
Better in summer
Fine scales on extensors
Flexors spared
Palmoplantar (hyperlinear palms)
Callus like lesion on knees and elbows
Follicular hyperkeratosis
3
Q
Predilection sites
A
Shins
Trunk
Lateral aspect of face
4
Q
Keratosis pilaris is seen on
A
Shoulder
Upper arm
Thigh
Buttocks
5
Q
Diagnosis
A
Biopsy
Family history
Clinical features
6
Q
Therapy
A
Topical urea compounds
Lactic acid
Corticosteroids useless
