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Flashcards in Acromegaly Deck (4)
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1

What is acromegaly?

Acromegaly is a condition that results from excess growth hormone (GH) after the growth plates have closed

2

What is gigantism?

A condition that results from excess growth hormone (GH) before the growth plates have closed (in childhood)

3

Outline the action of growth hormone

Growth hormone secretion from the somatotrophs of the anterior pituitary gland is stimulated by GHRH and GH acts on the liver to induce IGF-1 production which mediates all of the 'growth effects' of GH

4

How is GH secretion regulated?

Somatostatin inhibits the production of GHRH and GH, as does increasing levels of IGF-1.