Flashcards in Acromegaly Deck (4)
What is acromegaly?
Acromegaly is a condition that results from excess growth hormone (GH) after the growth plates have closed
What is gigantism?
A condition that results from excess growth hormone (GH) before the growth plates have closed (in childhood)
Outline the action of growth hormone
Growth hormone secretion from the somatotrophs of the anterior pituitary gland is stimulated by GHRH and GH acts on the liver to induce IGF-1 production which mediates all of the 'growth effects' of GH