Flashcards in Acute Pain Deck (13):
What medications used for mild pain have the greatest dose dependent risk for hepatic toxicity?
What medication used for mild pain can cause renal toxicity?
[True/False] To treat moderate pain you can use Tylenol w/ Codeine, Oxycodone or hydromorphone with APAP, and meperidine.
Meperidine is no longer recommended for moderate pain.
What are some second line therapies to treat moderate pain?
Pentazocine, Butorphanol, etc. (rarely used)
Characteristics of Tramadol
Onset is rapid
Half-life is 6-8 hours and for the active metabolite it is 7-9 hours.
Weak opiate and NE/SE reuptake inhibitor
What are some examples of potent mu receptor agonists that are used to treat severe pain?
When treating an opioid naive patient for severe pain what is the recommended starting dose?
When switching to a dose that is equivalent to another opioid what is recommended to do to account for variability in the conversion table?
Start at 75% of the equi-analgesic dose and provide something for breakthrough pain.
When titrating opioids what are the guidelines to minimize adverse effects?
Start with a low dose and titrate slowly.
When monitoring for respiratory depression in patients on opioids what do you need to have in uncomplicated patients?
Ramsey Score (Q4H)
What dose of naloxone do you give to a patient taking an opioid with a RR between 4-10?
This is 1/10 the dose of a rescue dose. You only give the full rescue dose of naloxone if the patient has stopped breathing.
How do you treat a patient that is in apnea (respiratory failure) due to an opioid?
Give the full rescue dose of naloxone (400mcg) every 2-3 minutes until the patient wakes up.
You need to stop the opioid.