Flashcards in Rheumatoid Arthritis Deck (13):
Inflamed, proliferating tissue
CD28 binds to what to become activated?
An ACR/EULAR score greater than ____ is a diagnosis of RA.
Non-Pharm Tx of RA
What HLA antigens put you at a higher risk of developing RA?
What are some comorbidities that put you at a higher risk for developing RA?
T1 and T2DM
Inflammatory lung disease
What are some protective environmental factors for RA?
Fish oil, olive oil
Infiltration of inflammatory cells into the synovial tissue
What CD factors must bind for T cells to be activated?
CD80/86 and CD28
What are some possible drug targets for RA?
IL-1 and IL-6
Joints involved in RA
Metacarpophalangeal, proximal interphalangeal, second through fifth metatarsophalangeal, thumb interphalangeal, wrist
Describe the difference between RA and osteoarthritis.
RA is morning stiffness longer than 30 minutes
RA doesn't increase with age
RA shows an increase in ESR
RA is symmetrical joint inflammation