Adrenal Gland Flashcards

(59 cards)

1
Q

Long arteries penetrate the capsule to get to…

A

the cortex and medulla

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2
Q

Short arteries form capillary beds in…

A

the cortex

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3
Q

Hormone producted in the zona glomerulosa (ZG)

A

aldosterone

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4
Q

Hormone producted in the zona fasiculata (ZF)

A

Cortisol

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5
Q

Hormone producted in the zona reticularis (ZR)

A

DHEA

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6
Q

Which layer shuttles byproducts to and from the SER and mitochondria to produce their hormone

A

ZG

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7
Q

Which layer has lots of lipid droplets within the cell

A

ZF

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8
Q

The cells in which layer contain secretion granules in the cortex of the gland

A

None because the hormone is secreted immediately after synthesis in the adrenal gland

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9
Q

Which layer is poorly stained

A

ZF (due to lipid droplets)

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10
Q

Which layer may contain lipofuscin pigment

A

ZR

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11
Q

Which layer is amphophilic (stains with acidic and basic dyes)

A

ZG

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12
Q

Which layer is acidophilic

A

ZR

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13
Q

Which layer contains an abundant number of lysosomes (EM)

A

ZR

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14
Q

Which layer contains lots of SER

A

All of them

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15
Q

Which layer contains tubule-vesicular mitochondrial cristae (long)

A

ZF

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16
Q

Which layer contains short tubular mito. crust (look like vesicles)

A

ZR

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17
Q

What layer contains elongated, broad and flat mito. cristae

A

ZG

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18
Q

Arrangement of cells in ZG

A

round balls

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19
Q

Arrangement of cells in ZF

A

straight cords

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20
Q

Arrangement of cells in ZR

A

branched cords

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21
Q

Which layer has straight sinusoidal capilaries

A

ZF

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22
Q

BV present in the medulla

A

post capillary venues and medullary veins

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23
Q

Outer most layer of the adrenal gland

A

capsule

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24
Q

What’s the name of the cells in the ZF with lots of lipid droplets

25
What lines sinusoidal capillaries
epithelium
26
Endothelium in sinusoidal capillaries is...
fenestrated with diaphragms
27
Name two structures that can be found on the capsule of the adrenal gland
Major BV of adrenal gland (i.e superior, middle, or inferior suprarenal a.) and autonomic nerve cells
28
If you find an arteriole in the ZR, what can we likely conclude it is?
Long artery
29
What is found between the capsule and ZG
smooth muscle
30
Other than Mitochondrial cristae what is another way to distinguish cells in the ZF from the ZG and ZR
lipid droplets
31
Which region of the adrenal cortex do NOT contain the medulla
tail
32
Are the layers of the adrenal gland of uniform thickness
no
33
Difference between post capillary venule and medullary vein
Medullary vein has several layers of smooth muscle surrounding it.
34
What makes medullary veins different from the suprarenal veins
medullary veins lack adventitia and have less smooth muscle
35
What are the two types of cells in the medulla
Darkly and lightly stained chromaffin cells
36
What do chromaffin cells stain with
Bichromate salts
37
What do the darkly stained chromaffin cells secrete
Noradrenaline
38
What do the lightly stained chromaffin cells secrete
adrenaline
39
What are the cells that signal the chromaffin cells to secrete their hormone
preganglionic sympathetic nerve fibers
40
How can you ID preganglionic sympathetic fibers in the medulla
Basophilic, Eccentric nucleus, prominent nucleolus, and satellite cells
41
Do chromaffin cells have secretion granules
yes
42
Color of chromaffin cells when stained with bichromate salts
brown (dark chromaffin) Red (light chromaffin)
43
Organelles in the chromaffin cells seen with EM
(organelles you would expect to see in secretory cells) RER, Golgi, secretion vesicles
44
Light chromaffin cells have (large/small) secretion granules
small
45
Dark chromaffin cells have (large/small) secretion granules
large
46
The cortex of the adrenal gland secretes (peptide/steroid) hormones
steroid (all derived from cholesterol)
47
Where is the cholestrol used to produce the steroid hormones in the adrenal gland stored
lipid droplets
48
Where are the steroid hormones produced in the adrenal gland modified
SER and mitochondria
49
Are steroid hormones produced in the adrenal cortex stored
no
50
What is norepinephrine made from
tyrosine
51
Describe the synthesis process of norepinephrine
Made from tyrosine in secretion granules, released into the cytoplasm, converted to epinephrine and resorbed and stored by granules.
52
Role of aldosterone in the body
absorption of Na+ and water by the kidney- raises blood pressure
53
Blank stimulated the release of aldosterone by the ZG
angiotensin 2
54
What stimulates the ZF to secrete cortisol
CRH, ACTH and gluconeogenesis by the liver
55
(Darkly or lightly) stain chromaffin cells have halos around their secretion granules
darkly
56
Physiological effects of norepinephrine
vasoconstriction (elevated blood pressure)
57
Physiological effects of epinephrine
Increased heart rate and output
58
What stimulated the secretion of norepiephrine/ epinephrine
preganglionic sympathetic nerve fibers (acetylcholine)
59
Where do the long and short cortical arteries drain
in medulla (medullary veins for long cortical arteries)