Respiratory System II Flashcards
(35 cards)
Is the secondary lobule of miller present of the lung or pleural tissue
pleura
What structures are held within the secondary lobules of miller
terminal bronchioles, respiratory bronchioles, alveolar ducts, alveolar sacs, and alveoli
Respiratory bronchioles are lined by… epithelium
ciliated cuboidal
T/F: The epithelium on the respiratory bronchiole is discontinuous
T, the epithelium is incomplete where the alveoli come off of the respiratory bronchiole
T/F: The alveoli coming off of the respiratory bronchioles are lined by the same type of epithelium
F, they are lined by simple squamous epithelium
In addition to the ciliated cuboidal cells, what other cells lie in the epithelium of the respiratory bronchioles
clara cell
A respiratory bronchiole divides to form two…
alveolar ducts
The alveolar duct is lined by…
simple squamous epithelium
What are interalveolar septa
walls between alveoli
Interalveolar septa are rich in…
BV and elastic fibers (responsible for elasticity of the lung)
Destruction of the inter alveolar septum is a sign of…
emphysema
Role of Pores of Kohn
help equilibrate pressure and aid in communication between adjacent alveoli
What passes in and out of pores of Kohn
dust cells
What are the two types of cells in the alveolus
Type I and II pneumocytes
What type of cell is the type I pneumocyte
simple squamous epithelial cell type
Describe the distribution of organelles in the type I pneumocyte (TIP)
Organelles are clustered around nucleus (leaving attenuated lateral surfaces)
TIP contains…vesicles to collect debris from the alveolar lumen to transfers them to…
pinocytotic…macrophages
T/F: The TIP doesn’t participate in the blood-air barrier
F
What is the function of the blood-air barrier
external respiration (therefore the barrier must be thin)
What is the blood air barrier comprised of
TIP, single basal lamina created by the fusion of the lamina of the alveolar epithelial and capillary endothelial cell, and the simple squamous epithelial cell of the capillary
T/F: TIPs comprise 95% of alveolar surface and are those more numerous than TIIPs?
F TIIPs are more numerous
Morphology of TIIP
Cuboidal cell with microvilli on apical surface
Key morphological feature of TIIP seen with EM
lamellar body
What is the sectretory product of the lamellar body
surfactant