Adrenergic Drugs

Question 1

enzyme from Tyrosine to DOPA

Answer 1

hydroxylase

Question 2

Reserpine

Answer 2

inhibits reuptake of Dopamine

Question 3

Cocaine, TCA

Answer 3

inhibits reuptake of NE

Question 4

Metyrosine

Answer 4

inhibits tyrosine hydroxylase

Question 5

no/weak β3 action

Answer 5

Epinephrine (Adrenaline)

Question 6

no/weak β2 action

Answer 6

Norepinephrine (Noradrenaline)

Question 7

no/weak α action

Answer 7

Isoproterenol (Isoprenaline)

Question 8

α1 receptor

Answer 8

Gq

smooth muscles, glands

contraction, secretion

Question 9

α2 receptor

Answer 9

Gi

nerve endings
decreased transmitter release

smooth muscle
contraction

Question 10

β1 receptor

Answer 10

Gs

cardiac muscle

increased HR, renin, force

Question 11

β2 receptor

Answer 11

Gs

smooth muscle, liver, heart

relax smooth muscle, increased HR and force

Question 12

nonselective α agonists

Answer 12

NE

Question 13

α1-selective agonists

Answer 13

phenylephrine

Question 14

α2-selective agonists

Answer 14

clondine

Question 15

nonselective β agonists

Answer 15

isoproterenol

Question 16

β1-selective agonists

Answer 16

dobutamine

Question 17

β2-selective agonists

Answer 17

albuterol

Question 18

Vasoconstrictor agents

Answer 18

Phenylephrine

Question 19

Cardiac stimulants

Answer 19

Dobutamine

Dopamine

Question 20

Bronchodilators

Answer 20

Albuterol

Question 21

Nasal decongestants

Answer 21

Phenylephrine

Xylometazoline

Question 22

CNS stimulants

Answer 22

Amphetamine

Question 23

Uterine relaxant (Tocolytics)

Answer 23

Ritodrine

Question 24

α1 effects

Answer 24

↑ TPR
↑ BP
reflex bradycardia
mydriasis

Question 25

Phenylephrine

Answer 25

nasal decongestant & ophthalmic use mydriasis without cycloplegia

Question 26

Methyldopa use

Answer 26

HTN in Pregnancy

Question 27

Salmeterol, albuterol use

Answer 27

bronchial asthma, COPD

Question 28

Ritodrine & terbutaline use

Answer 28

premature labor

Question 29

Norepinephrine (noradrenaline) effects

Answer 29

↑ HR | No β2 effect

Question 30

Epinephrine (adrenaline) effects

Answer 30

↓TPR ↓ BP- β2 Biphasic response on BP

Question 31

Dopamine

Answer 31

adrenergic agonist Use: cardiogenic (renal vasodilation via D1 receptors) or septic shock & congestive heart failure (CHF)

Question 32

Fenoldopam use

Answer 32

hypertensive emergency

Question 33

Dobutamine

Answer 33

selective β1 agonist Used in severe CHF

Question 34

Ephedrine

Answer 34

↑ release of NE use: hypotension Tachyphylaxis

Question 35

Amphetamine uses

Answer 35

narcolepsy and attention deficit hyperkinetic | disorder

Question 36

contraindications for the use of adrenergic agonists

Answer 36

``` Ischemic heart disease Hypertension Diabetes mellitus Pheochromocytoma Hyperthyroidism ```